BTLA Protein (AA 31-150) (Fc Tag)
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- 抗原 See all BTLA 蛋白
- BTLA (B and T Lymphocyte Associated (BTLA))
- 蛋白类型
- Recombinant
- 产品特性
- AA 31-150
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宿主
- 人
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资源
- 人细胞
- 标记
- This BTLA protein is labelled with Fc Tag.
- 原理
- Recombinant Human B- and T-Lymphocyte Attenuator/BTLA/CD272 (C-Fc)
- 序列
- KESCDVQLYI KRQSEHSILA GDPFELECPV KYCANRPHVT WCKLNGTTCV KLEDRQTSWK EEKNISFFIL HFEPVLPNDN GSYRCSANFQ SNLIESHSTT LYVTGKQNEL SDTAGREINL VDDIEGRMDE PKSCDKTHTC PPCPAPELLG GPSVFLFPPK PKDTLMISRT PEVTCVVVDV SHEDPEVKFN WYVDGVEVHN AKTKPREEQY NSTYRVVSVL TVLHQDWLNG KEYKCKVSNK ALPAPIEKTI SKAKGQPREP QVYTLPPSRE EMTKNQVSLT CLVKGFYPSD IAVEWESNGQ PENNYKTTPP VLDSDGSFFL YSKLTVDKSR WQQGNVFSCS VMHEALHNHY TQKSLSLSPG K
- 产品特性
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Recombinant Human B- and T-Lymphocyte Attenuator/BTLA/CD272 (C-Fc)
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product BTLA 蛋白
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B and T Lymphocyte Associated (BTLA) (AA 31-150) protein (Fc Tag)
BTLA 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
B and T Lymphocyte Associated (BTLA) (AA 31-150) protein (His-Avi Tag)BTLA 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
B and T Lymphocyte Associated (BTLA) protein (His-Avi Tag,Biotin)BTLA 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
B and T Lymphocyte Associated (BTLA) protein (mFc-His Tag)BTLA 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
B and T Lymphocyte Associated (BTLA) (AA 30-176) protein (His tag)BTLA 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
B and T Lymphocyte Associated (BTLA) protein (mFc Tag)BTLA 宿主: 人 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE.
B and T Lymphocyte Associated (BTLA) (AA 190-289) protein (GST tag)BTLA 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
B and T Lymphocyte Associated (BTLA) (AA 25-289) protein (His tag)BTLA 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant SDS, Func
B and T Lymphocyte Associated (BTLA) (Active) protein (Fc Tag)BTLA 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active
B and T Lymphocyte Associated (BTLA) (Active) protein (Fc Tag,ECD)BTLA 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- 4 °C/-20 °C/-80 °C
- 储存方法
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- BTLA (B and T Lymphocyte Associated (BTLA))
- 别名
- BTLA (BTLA 产品)
- 别名
- BTLA Protein, BTLA1 Protein, CD272 Protein, A630002H24 Protein, B and T lymphocyte associated Protein, BTLA Protein, Btla Protein
- 背景
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Recombinant Human B-andT-lymphocyte attenuator/BTLA/CD272 is produced by our mammalian expression system. The target protein is expressed with sequence (Lys31-Leu150) of Human BTLA fused with FC and polyhistidine tag at the C-terminus.
B- and T-Lymphocyte Attenuator (BTLA) is a single-pass type I membrane protein containing 1 Ig-like V-type (immunoglobulin-like) domain. BTLA expression is induced during activation of T cells, and BTLA remains expressed on Th1 cells but not Th2 cells. Like PD1 and CTLA4, BTLA interacts with a B7 homolog, B7H4. However, unlike PD-1 and CTLA-4, BTLA displays T-Cell inhibition via interaction with tumor necrosis family receptors (TNF-R), not just the B7 family of cell surface receptors. BTLA is a lymphocyte inhibitory receptor that inhibits lymphocytes during immune response. BTLA also is a ligand for tumor necrosis factor (receptor) superfamily, member 14 (TNFRSF14), also known as herpes virus entry mediator (HVEM). BTLA-HVEM complexes negatively regulate T-cell immune responses. - 分子量
- 40.8 kDa
- UniProt
- Q7Z6A9
- 途径
- Cancer Immune Checkpoints
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