BTLA Protein (Fc Tag,ECD)
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- 抗原 See all BTLA 蛋白
- BTLA (B and T Lymphocyte Associated (BTLA))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 大鼠
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资源
- HEK-293 Cells
- 标记
- This BTLA protein is labelled with Fc Tag,ECD.
- 原理
- Recombinant Rat BTLA/CD272 Protein (ECD, Fc Tag)(Active)
- 序列
- Ala6-Tyr183
- 产品特性
- A DNA sequence encoding the rat Btla (NP_998795.1) (Ala6-Tyr183) was expressed with the Fc region of mouse IgG1 at the C-terminus.
- 纯度
- > 90 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg protein as determined by the LAL method.
- Biological Activity Comment
- 1. Measured by its binding ability in a functional ELISA.2. Immobilized rat BTLA-mFc at 10 μg/mL (100 μL/well) can bind mouse HVEM-Fch . The EC50 of mouse EFNA5-Fc is 6.2-14.4 ng/mL.
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- Discover our top product BTLA 蛋白
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B and T Lymphocyte Associated (BTLA) (AA 31-150) protein (Fc Tag)
BTLA 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
B and T Lymphocyte Associated (BTLA) (AA 31-150) protein (His-Avi Tag)BTLA 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
B and T Lymphocyte Associated (BTLA) protein (His-Avi Tag,Biotin)BTLA 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
B and T Lymphocyte Associated (BTLA) protein (mFc-His Tag)BTLA 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
B and T Lymphocyte Associated (BTLA) (AA 30-176) protein (His tag)BTLA 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
B and T Lymphocyte Associated (BTLA) protein (mFc Tag)BTLA 宿主: 人 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE.
B and T Lymphocyte Associated (BTLA) (AA 190-289) protein (GST tag)BTLA 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
B and T Lymphocyte Associated (BTLA) (AA 25-289) protein (His tag)BTLA 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant SDS, Func
B and T Lymphocyte Associated (BTLA) (Active) protein (Fc Tag)BTLA 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- BTLA (B and T Lymphocyte Associated (BTLA))
- 别名
- BTLA/CD272 (BTLA 产品)
- 别名
- BTLA Protein, BTLA1 Protein, CD272 Protein, A630002H24 Protein, B and T lymphocyte associated Protein, BTLA Protein, Btla Protein
- 背景
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Background: BTLA is a inhibitory molecule which belongs to the Ig superfamily. It down-modulates immune responses. As such, reagents that regulate the binding of BTLA to its ligand or alter BTLA signaling have significant therapeutic promise. BTLA is crucial to understand the mechanism(s) of action of these antibodies before attempting clinical applications. BTLA is not expressed by naive T cells, but it is induced during activation and remains expressed on T helper type 1 (T(H)1) but not T(H)2 cells. BTLA is a third inhibitory receptor on T lymphocytes with similarities to cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and programmed death 1 (PD-1).Immune CheckpointImmune Checkpoint Targets Co-inhibitory Immune Checkpoint Targets Immunotherapy Cancer Immunotherapy Targeted Therapy
Synonym: BTLA
- 分子量
- 43.4 kDa
- NCBI登录号
- NP_998795
- 途径
- Cancer Immune Checkpoints
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