Crystallography grade
PCSK9
宿主: 小鼠
宿主: Insect Cells
Recombinant
>95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
WB, SDS, ELISA, Crys
限制
仅限研究用
状态
Liquid
缓冲液
Supplied as a 0.2 μm filtered solution of 50 mM HEPES,150 mM NaCl,20 % Glycerol, pH 7.4.
储存条件
-80 °C
储存方法
Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
有效期
6 months
抗原
PCSK9
(Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9))
别名
Proprotein Convertase Subtilisin/Kexin Type 9/PCSK9 (PCSK9 产品)
别名
FH3 Protein, HCHOLA3 Protein, LDLCQ1 Protein, NARC-1 Protein, NARC1 Protein, PC9 Protein, AI415265 Protein, AI747682 Protein, Narc1 Protein, proprotein convertase subtilisin/kexin type 9 Protein, proprotein convertase subtilisin/kexin type 9 L homeolog Protein, PCSK9 Protein, pcsk9.L Protein, pcsk9 Protein, Pcsk9 Protein
背景
Recombinant Rhesus Proprotein Convertase Subtilisin/Kexin Type 9/PCSK9 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Q31-Q692) of Rhesus PCSK9 fused with a polyhistidine tag at the C-terminus. Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a secretory subtilase belonging to the proteinase K subfamily. PCSK9 is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the ER , the pro domain and mature chain secrete together through noncovalent interactions. PCSK9 binds with low-density lipoprotein receptor (LDLR) and plays a major regulatory role in cholesterol homeostasis. PCSK9 also plays a role in the neural development.