FGF23 Protein (AA 1-251) (Fc Tag)
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- 抗原 See all FGF23 蛋白
- FGF23 (Fibroblast Growth Factor 23 (FGF23))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 1-251
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This FGF23 protein is labelled with Fc Tag.
- 应用范围
- SDS-PAGE (SDS)
- 交叉反应
- 人
- 产品特性
- Signal peptide and human FGF-23 (aa 1-251) are fused at the C-terminus to the Fc portion of human IgG1.
- 纯度
- >90 % (SDS-PAGE)
- 过滤
- 0.2 μm filtered
- 内毒素水平
- <0.1EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product FGF23 蛋白
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Fibroblast Growth Factor 23 (FGF23) (AA 25-251) (Active) protein (His tag)
FGF23 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） > 90 % AcA, CC Active
Fibroblast Growth Factor 23 (FGF23) (AA 25-251) protein (His tag)FGF23 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Fibroblast Growth Factor 23 (FGF23) (AA 1-251) protein (GST tag)FGF23 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Fibroblast Growth Factor 23 (FGF23) (AA 25-179) protein (His tag)Crystallography grade FGF23 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Fibroblast Growth Factor 23 (FGF23) (AA 180-251) protein (His tag)Crystallography grade FGF23 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Fibroblast Growth Factor 23 (FGF23) (AA 25-251) protein (His tag)Crystallography grade FGF23 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Fibroblast Growth Factor 23 (FGF23) (AA 25-251) protein (His tag)Crystallography grade FGF23 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Fibroblast Growth Factor 23 (FGF23) (AA 25-251), (full length) protein (His tag)FGF23 宿主: 大鼠 宿主: 酵母菌 Recombinant > 90 % ELISA
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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Activates ERK and FRS2alpha phosphorylation in Klotho expressing cells.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- 0.2μm-filtered solution in PBS.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Working aliquots are stable for up to 3 months when stored at -20°C. - 有效期
- 3 months
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- 抗原
- FGF23 (Fibroblast Growth Factor 23 (FGF23))
- 别名
- FGF-23 (FGF23 产品)
- 别名
- FGF23 Protein, ADHR Protein, FGFN Protein, HPDR2 Protein, HYPF Protein, PHPTC Protein, fibroblast growth factor 23 Protein, fgf23 Protein, FGF23 Protein, Fgf23 Protein
- 背景
- FGF-23 (Fibroblast growth factor 23) is a regulator of phosphate homeostasis. It upregulates EGR1 expression in the presence of KLBy. Acts directly on the parathyroid to decrease PTH secretion. Regulates the vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization. Defects in FGF-23 are the cause of autosomal dominant hypophosphataemic rickets (ADHR) and of hyperphosphatemic familial tumoral calcinosis (HFTC).
- 分子量
- ~60kDa (SDS-PAGE, full-length) FGF23 is cleaved between arg179 and ser 180 (~40kDa).
- UniProt
- Q9GZV9
- 途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Negative Regulation of Hormone Secretion
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