SERPING1 Protein (His tag)
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- 抗原 See all SERPING1 蛋白
- SERPING1 (Serpin Peptidase Inhibitor, Clade G (C1 Inhibitor), Member 1 (SERPING1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This SERPING1 protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 纯度
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product SERPING1 蛋白
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- 说明
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Synonyms: Plasma protease C1 inhibitor, C1IN, C1INH, C1NH, HAE1, HAE2
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.5 mg/ml (determined by Bradford assay)
- 缓冲液
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea, 10% glycerol
- 储存条件
- 4 °C
- 储存方法
- Avoid repeated freezing and thawing cycles.
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- 抗原
- SERPING1 (Serpin Peptidase Inhibitor, Clade G (C1 Inhibitor), Member 1 (SERPING1))
- 别名
- SERPING1 (SERPING1 产品)
- 别名
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- 背景
- Plasma protease C1 inhibitor, also known as SERPING1, is a member of the serpin superfamily of serine protease inhibitors. SERPING1 regulates the activation of complement factor C1 as well as the activity of activated C1 by coupling with the active catalytic site at the light chains of C1r and C1s. Therefore, it plays an important role in regulating activation of both the complement and contact systems. SERPING1 deficiency results in hereditary angioedema, which is characterized by recurrent episodes of localized angioedema of the skin, gastrointestinal mucosa or upper respiratory mucosa. Recombinant human SERPING1 protein, fused to His-tag at N-terminus, was expressed in E.coli.
- 分子量
- 55.1 kDa (499aa)
- NCBI登录号
- NP_001027466
- 途径
- Complement System
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