SERPING1 Protein (His tag)
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- 抗原 See all SERPING1 蛋白
- SERPING1 (Serpin Peptidase Inhibitor, Clade G (C1 Inhibitor), Member 1 (SERPING1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 人细胞
- 标记
- This SERPING1 protein is labelled with His tag.
- 原理
- Recombinant Human SerpinG1/C1IN Protein (His Tag)
- 序列
- Asn23-Ala500
- 产品特性
- Recombinant Human Serine Protease Inhibitor-clade G1 is produced by our Mammalian expression system and the target gene encoding Asn23-Ala500 is expressed with a 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product SERPING1 蛋白
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Serpin Peptidase Inhibitor, Clade G (C1 Inhibitor), Member 1 (SERPING1) (AA 1-500) protein (GST tag)
SERPING1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Serpin Peptidase Inhibitor, Clade G (C1 Inhibitor), Member 1 (SERPING1) protein (His tag)SERPING1 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
Serpin Peptidase Inhibitor, Clade G (C1 Inhibitor), Member 1 (SERPING1) proteinSERPING1 宿主: 人 宿主: Human Native >95 %
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- SERPING1 (Serpin Peptidase Inhibitor, Clade G (C1 Inhibitor), Member 1 (SERPING1))
- 别名
- SerpinG1/C1IN (SERPING1 产品)
- 别名
- fb64f02 Protein, im:7159527 Protein, si:dkeyp-110g5.2 Protein, wu:fb60c09 Protein, wu:fb62a08 Protein, wu:fb64f02 Protein, LOC100136072 Protein, C1-INH Protein, C1INH Protein, C1nh Protein, C1IN Protein, C1NH Protein, HAE1 Protein, HAE2 Protein, serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 Protein, C1 inhibitor Protein, serpin family G member 1 Protein, serine (or cysteine) peptidase inhibitor, clade G, member 1 Protein, serping1 Protein, LOC100136072 Protein, SERPING1 Protein, Serping1 Protein
- 背景
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Background: As protease inhibitors, serpins have an array of functions including regulating blood clotting, the complement pathway, extracellular matrix remodeling, and cell motility. Serpin G1 is a serine protease inhibitor protein. It is the largest member among the serpin class of proteins. Remarkably, Serpin G1 has a 2-domain structure, unlike most family members. The C-terminal serpin domain is similar to other serpins, and this part of Serpin G1 provides the inhibitory activity. The N-terminal domain is not essential for Serpin G1 to inhibit proteinases and has no similarity to other proteins. The main function of Serpin G1 is the inhibition of the complement system to prevent spontaneous activation. Serpin G1 is an acute phase protein and circulates in blood at levels of around 0.25g/L, whose levels rise 2-fold during inflammation. Although named after its complement inhibitory activity, Serpin G1 also inhibits proteinases of the fibrinolytic, clotting, and kinin pathways. Most notably, Serpin G1 play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. It is also the most important physiological inhibitor of fXIIa, chymotrypsin and plasma kallikrein.
Synonym: Plasma Protease C1 Inhibitor, C1 Inh, C1Inh, C1 Esterase Inhibitor, C1-Inhibiting Factor, Serpin G1, SERPING1, C1IN, C1NH,HAE1,HAE2
- 分子量
- 53.9 kDa
- UniProt
- P05155
- 途径
- Complement System
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