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PIM1 Protein (His tag)

PIM1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % by SDS - PAGE SDS
产品编号 ABIN7280180
发货至: 中国
  • 抗原 See all PIM1 蛋白
    PIM1 (Pim-1 Oncogene (PIM1))
    蛋白类型
    Recombinant
    宿主
    • 9
    • 3
    • 2
    • 1
    • 1
    资源
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This PIM1 protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    纯化方法
    purified by chromatography
    纯度
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product PIM1 蛋白
  • 说明

    Synonyms: Non-specific serine/threonine protein kinase, PIM

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/ml (determined by Bradford assay)
    缓冲液
    20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 10% glycerol, 1 MM DTT
    储存条件
    4 °C
    储存方法
    Avoid repeated freezing and thawing cycles.
  • 抗原
    PIM1 (Pim-1 Oncogene (PIM1))
    别名
    Pim1 (PIM1 产品)
    别名
    PIM Protein, Pim-1 Protein, PIM1 Protein, pim Protein, pim-1 Protein, pim3 Protein, Pim-1 proto-oncogene, serine/threonine kinase Protein, proviral integration site 1 Protein, Pim-1 proto-oncogene, serine/threonine kinase L homeolog Protein, PIM1 Protein, Pim1 Protein, pim1 Protein, pim1.L Protein
    背景
    PIM1 belongs to the Ser/Thr protein kinase family, and PIM subfamily. This protein is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons. Recombinant human Pim1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
    分子量
    31.4 kDa (274aa) confirmed by MALDI-TOF
    NCBI登录号
    NP_002639
    途径
    Glycosaminoglycan Metabolic Process
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