PIM1 产品
(Pim-1 Oncogene (PIM1))
Categories
The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons (PMIDs:16186805, 1825810).[provided by RefSeq, Aug 2011].
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Featured PIM1 Categories
PIM1 抗体
High quality antibodies with extensive validation data.
PIM1 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
PIM1 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PIM1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (4)
Cat. No.
ABIN7429160
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (4)
Cat. No.
ABIN562235
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (4)
Cat. No.
ABIN7269375
Quantity
100 μL
Datasheet
Datasheet
Recommended PIM1 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958588
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN1503732
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN1503733
Quantity
96 tests
Datasheet
Datasheet
Recommended PIM1 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Insect cells (Sf21)
Validations
- (2)
Cat. No.
ABIN5570464
Quantity
5 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect cells (Sf9)
Validations
- (2)
Cat. No.
ABIN5570463
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7124452
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our PIM1 Products
: "PIM-1 contributes to the malignancy of pancreatic cancer and displays diagnostic and prognostic value." in: Journal of experimental & clinical cancer research : CR, Vol. 35, Issue 1, pp. 133, (2017) (PubMed).: "Patterns and Significance of PIM Kinases in Urothelial Carcinoma." in: Applied immunohistochemistry & molecular morphology : AIMM, Vol. 23, Issue 10, pp. 717-23, (2016) (PubMed).
: "PIM1 polymorphism and PIM1 expression as predisposing factors of esophageal squamous cell carcinoma in the Asian population." in: OncoTargets and therapy, Vol. 9, pp. 2919-25, (2016) (PubMed).
: "Molecular markers predicting lymph node metastasis in early esophageal cancer." in: Histology and histopathology, pp. 11618, (2015) (PubMed).
: "Pim1 kinase is upregulated in glioblastoma multiforme and mediates tumor cell survival. ..." in: Neuro-oncology, Vol. 17, Issue 2, pp. 223-42, (2015) (PubMed).
: "Human CD180 Transmits Signals via the PIM-1L Kinase." in: PLoS ONE, Vol. 10, Issue 11, pp. e0142741, (2015) (PubMed).
: "Phenotype profiling of primary testicular diffuse large B-cell lymphomas." in: Hematological oncology, Vol. 32, Issue 2, pp. 72-81, (2014) (PubMed).
: "Pim-1: A new biomarker in pulmonary arterial hypertension." in: Pulmonary circulation, Vol. 3, Issue 1, pp. 74-81, (2013) (PubMed).
: "Phosphorylation of the androgen receptor by PIM1 in hormone refractory prostate cancer." in: Oncogene, Vol. 32, Issue 34, pp. 3992-4000, (2013) (PubMed).
: "PIM1 gene cooperates with human BCL6 gene to promote the development of lymphomas." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 15, pp. 5735-9, (2012) (PubMed).
Synonyms and alternative names related to PIM1
Pim-1 proto-oncogene, serine/threonine kinase (PIM1), proviral integration site 1 (Pim1), Pim-1 proto-oncogene, serine/threonine kinase (Pim1), Pim-1 proto-oncogene, serine/threonine kinase (pim1), Pim-1 proto-oncogene, serine/threonine kinase L homeolog (pim1.L), PIM, pim, Pim-1, pim-1, PIM1, pim3Protein level used designations for PIM1
- Oncogene PIM1
- pim-1 kinase 44 kDa isoform
- pim-1 oncogene (proviral integration site 1)
- proto-oncogene serine/threonine-protein kinase pim-1
- serine/threonine-protein kinase pim-1
- pim-1 oncogene
- non-specific serine/threonine protein kinase
- proto-oncogene serine/threonine-protein kinase Pim-1
- proviral integration site 1
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