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PIM3 产品

(Pim-3 Oncogene (PIM3))
The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is overexpressed in hematological and epithelial tumors and is associated with MYC coexpression. It plays a role in the regulation of signal transduction cascades, contributing to both cell proliferation and survival, and provides a selective advantage in tumorigenesis. [provided by RefSeq, Jun 2012].

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Featured PIM3 Categories

PIM3 抗体

High quality antibodies with extensive validation data.

PIM3 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

PIM3 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PIM3 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, WB, IHC, IF
Validations
  • (4)
Cat. No. ABIN7169149
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (5)
  • (3)
Cat. No. ABIN391253
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (2)
Cat. No. ABIN531803
Quantity 100 μg
Datasheet Datasheet

Recommended PIM3 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958589
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6231830
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6231829
Quantity 96 tests
Datasheet Datasheet

Recommended PIM3 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect cells (Sf21)
Validations
  • (2)
Cat. No. ABIN5570473
Quantity 5 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1315106
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3086163
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our PIM3 Products

Ishikawa, Senba, Hashimoto, Imaizumi, Mori: "Expression and significance of Pim-3 kinase in adult T-cell leukemia." in: European journal of haematology, Vol. 99, Issue 6, pp. 495-504, (2018) (PubMed).

Egli, Zajonz, Burger, Schweighoffer: "Human CD180 Transmits Signals via the PIM-1L Kinase." in: PLoS ONE, Vol. 10, Issue 11, pp. e0142741, (2015) (PubMed).

Decker, Finter, Forde, Kissel, Schwaller, Mack, Kuhn, Gray, Follo, Jumaa, Burger, Zirlik, Pfeifer, Miduturu, Eibel, Veelken, Dierks: "PIM kinases are essential for chronic lymphocytic leukemia cell survival (PIM2/3) and CXCR4-mediated microenvironmental interactions (PIM1)." in: Molecular cancer therapeutics, Vol. 13, Issue 5, pp. 1231-45, (2014) (PubMed).

Hu, Li, Li: "MARVELD1 Inhibits Nonsense-Mediated RNA Decay by Repressing Serine Phosphorylation of UPF1." in: PLoS ONE, Vol. 8, Issue 6, pp. e68291, (2013) (PubMed).

Brault, Menter, Obermann, Knapp, Thommen, Schwaller, Tzankov: "PIM kinases are progression markers and emerging therapeutic targets in diffuse large B-cell lymphoma." in: British journal of cancer, Vol. 107, Issue 3, pp. 491-500, (2012) (PubMed).

Chen, Redkar, Bearss, Wierda, Gandhi: "Pim kinase inhibitor, SGI-1776, induces apoptosis in chronic lymphocytic leukemia cells." in: Blood, Vol. 114, Issue 19, pp. 4150-7, (2009) (PubMed).

Cheng, Weidner-Glunde, Varjosalo, Rainio, Lehtonen, Schulz, Koskinen, Taipale, Ojala: "KSHV reactivation from latency requires Pim-1 and Pim-3 kinases to inactivate the latency-associated nuclear antigen LANA." in: PLoS pathogens, Vol. 5, Issue 3, pp. e1000324, (2009) (PubMed).

Mikkers, Nawijn, Allen, Brouwers, Verhoeven, Jonkers, Berns: "Mice deficient for all PIM kinases display reduced body size and impaired responses to hematopoietic growth factors." in: Molecular and cellular biology, Vol. 24, Issue 13, pp. 6104-15, (2004) (PubMed).

Eichmann, Yuan, Bréant, Alitalo, Koskinen: "Developmental expression of pim kinases suggests functions also outside of the hematopoietic system." in: Oncogene, Vol. 19, Issue 9, pp. 1215-24, (2000) (PubMed).

Synonyms and alternative names related to PIM3

Serine/threonine-protein kinase Pim-3 (pim3), Pim-3 proto-oncogene, serine/threonine kinase S homeolog (pim3.S), Pim-3 proto-oncogene, serine/threonine kinase (PIM3), Pim-3 proto-oncogene, serine/threonine kinase (Pim3), pim-3 oncogene (PIM3), proviral integration site 3 (Pim3), BC026639, Kid1, pim-3, pim1-a

Protein level used designations for PIM3

  • serine/threonine protein kinase pim-3
  • non-specific serine/threonine protein kinase
  • serine/threonine-protein kinase pim-3
  • serine/threonine kinase Pim-3
  • kinase induced by depolarization
  • protein kinase Kid-1
  • proviral integration site 3
  • serine threonine kinase pim3
  • KID-1/kinase induced by depolarization
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