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TANK Protein (His tag)

TANK 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 85 % by SDS - PAGE SDS
产品编号 ABIN1098532
发货至: 中国
  • 抗原 See all TANK 蛋白
    TANK (TRAF Family Member-Associated NFKB Activator (TANK))
    蛋白类型
    Recombinant
    宿主
    • 7
    • 1
    资源
    • 3
    • 2
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This TANK protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    纯化方法
    purified by chromatography
    纯度
    > 85 % by SDS - PAGE
    Top Product
    Discover our top product TANK 蛋白
  • 说明

    Synonyms: TRAF family member-associated NFkappa-B activator isoform a, I-TRAF, TRAF2

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/ml (determined by Bradford assay)
    缓冲液
    20 mM Tris-HCl buffer (pH 8.0) containing 0.2 M NaCl, 50% glycerol, 2 mM DTT
    储存条件
    4 °C
    储存方法
    Avoid repeated freezing and thawing cycles.
  • 抗原
    TANK (TRAF Family Member-Associated NFKB Activator (TANK))
    别名
    TANK (TANK 产品)
    别名
    I-TRAF Protein, ITRAF Protein, TRAF2 Protein, C86182 Protein, E430026L09Rik Protein, zgc:153048 Protein, i-traf Protein, tank Protein, traf2 Protein, TRAF family member associated NFKB activator Protein, TRAF family member-associated Nf-kappa B activator Protein, TRAF family member-associated NFKB activator Protein, TRAF family member associated NFKB activator L homeolog Protein, TANK Protein, Tank Protein, tank Protein, tank.L Protein
    背景
    TANK, also known as TRAF interacting protein, is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby proposing that this protein is an inhibitor of TRAF function that regulates TRAF protein activity by sequestering TRAFs in a latent state in the cytoplasm. Overexpression of TANK inhibits TRAF2-mediated NF-Kappa-B activation signaled by CD40 and both TNF receptors and inhibits LMP1-mediated NF-kappa-B activation by blocking the association of TRAF2 with LMP1. Recombinant human TANK protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
    分子量
    50.2 kDa (448aa)
    NCBI登录号
    NP_001186064
    途径
    p53 Pathway, TLR signaling, Activation of Innate immune Response
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