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nectin-3 Protein (AA 58-366) (His tag)

NECTIN3 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN1097209
发货至: 中国
  • 抗原 See all nectin-3 (NECTIN3) 蛋白
    nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))
    蛋白类型
    Recombinant
    产品特性
    AA 58-366
    宿主
    • 17
    • 4
    资源
    • 8
    • 4
    • 4
    • 3
    • 1
    • 1
    人细胞
    标记
    This nectin-3 protein is labelled with His tag.
    原理
    Recombinant Human Nectin-3/PVRL3/CD113 (C-6His)
    序列
    GPIIVEPHVT AVWGKNVSLK CLIEVNETIT QISWEKIHGK SSQTVAVHHP QYGFSVQGEY QGRVLFKNYS LNDATITLHN IGFSDSGKYI CKAVTFPLGN AQSSTTVTVL VEPTVSLIKG PDSLIDGGNE TVAAICIAAT GKPVAHIDWE GDLGEMESTT TSFPNETATI ISQYKLFPTR FARGRRITCV VKHQALEKDI RYSFILDIQY APEVSVTGYD GNWFVGRKGV NLKCNADANP PPFKSVWSRL DGQWPDGLLA SDNTLHFVHP LTFNYSGVYI CKVTNSLGQR SDQKVIYISA YNSVASLNCV DHHHHHH
    产品特性
    Recombinant Human Nectin-3 is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Gly58-Cys366) of Human PVRL3 fused with a polyhistidine tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    过滤
    0.2 μm filtered
    内毒素水平
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product NECTIN3 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
    注意事项
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    储存条件
    4 °C/-20 °C/-80 °C
    储存方法
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    3 months
  • 抗原
    nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))
    别名
    nectin-3 (NECTIN3 产品)
    别名
    PVRL3 Protein, CD113 Protein, CDW113 Protein, NECTIN-3 Protein, PPR3 Protein, PRR3 Protein, PVRR3 Protein, 2610301B19Rik Protein, 3000002N23Rik Protein, 4921513D19Rik Protein, AA407785 Protein, AU016832 Protein, AW538082 Protein, nectin cell adhesion molecule 3 Protein, poliovirus receptor-related 3 Protein, Nectin3 Protein, NECTIN3 Protein, PVRL3 Protein, nectin3 Protein
    Sub Type
    Fusionprotein
    背景
    Nectin-3 is a type I transmembrane glycoprotein that belongs to the nectin family. Its precursor is 549 amino acids in length and contains an extended signal sequence of 57 amino acids, an extracellular domain (ECD) of 347 amino acids, a transmembrane segment of 21 amino acids, and a cytoplasmic region of 124 amino acids. It is predominantly expressed in testis and placenta as well as in various cell lines, including epithelial cell lines. Nectin-3 plays a role in cell-cell adhesion through heterophilic trans-interactions with nectin-like proteins or nectins, such as trans-interaction with PVRL2/Nectin-2 at Sertoli-spermatid junctions. Nectin-3 is also involved in the formation of cell-cell junctions, including adherens junctions and synapses.
    Alternative Names: Poliovirus Receptor-Related Protein 3, CDw113, Nectin-3, CD113, PVRL3, PRR3
    分子量
    34.96 kDa
    UniProt
    Q9NQS3
    途径
    Cell-Cell Junction Organization
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