PVRL2 Protein (AA 32-360) (His tag)
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- 抗原 See all PVRL2 蛋白
- PVRL2 (Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2))
- 蛋白类型
- Recombinant
- 产品特性
- AA 32-360
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宿主
- 人
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资源
- 人细胞
- 标记
- This PVRL2 protein is labelled with His tag.
- 原理
- Recombinant Human Poliovirus Receptor-Related Protein 2/PVRL2/CD112 (C-6His)
- 序列
- QDVRVQVLPE VRGQLGGTVE LPCHLLPPVP GLYISLVTWQ RPDAPANHQN VAAFHPKMGP SFPSPKPGSE RLSFVSAKQS TGQDTEAELQ DATLALHGLT VEDEGNYTCE FATFPKGSVR GMTWLRVIAK PKNQAEAQKV TFSQDPTTVA LCISKEGRPP ARISWLSSLD WEAKETQVSG TLAGTVTVTS RFTLVPSGRA DGVTVTCKVE HESFEEPALI PVTLSVRYPP EVSISGYDDN WYLGRTDATL SCDVRSNPEP TGYDWSTTSG TFPTSAVAQG SQLVIHAVDS LFNTTFVCTV TNAVGMGRAE QVIFVRETPR ASPRDVGPLV DHHHHHH
- 产品特性
- Recombinant Human Poliovirus Receptor-Related Protein 2/PVRL2 is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Gln32-Leu360) of Human CD112 fused with a polyhistidine tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product PVRL2 蛋白
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Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2) (AA 32-360) protein (His-Avi Tag)
PVRL2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2) (AA 32-351) protein (His tag)PVRL2 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2) (AA 32-360) protein (Fc Tag)PVRL2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2) protein (His-Avi Tag,Biotin)PVRL2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2) (AA 32-360) (Active) protein (Fc Tag)PVRL2 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Func Active
Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2) (AA 32-360) (Active) protein (His tag)PVRL2 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Func Active
Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2) (AA 32-360) (Active) protein (Fc Tag,AVI tag,Biotin)PVRL2 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2) (AA 43-182) protein (His tag)PVRL2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2) (AA 1-479) protein (GST tag)PVRL2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2) protein (His tag)PVRL2 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- 4 °C/-20 °C/-80 °C
- 储存方法
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. - 有效期
- 3 months
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- 抗原
- PVRL2 (Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2))
- 别名
- cd112 (PVRL2 产品)
- 别名
- prr2 Protein, AI325026 Protein, AI987993 Protein, Cd112 Protein, MPH Protein, Pvr Protein, Pvs Protein, nectin-2 Protein, CD112 Protein, HVEB Protein, PRR2 Protein, PVRR2 Protein, nectin cell adhesion molecule 2 Protein, Nectin2 Protein, NECTIN2 Protein
- Sub Type
- Fusionprotein
- 背景
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CD112 is a type I transmembrane glycoprotein belonging to the Immunoglobulin superfamily. It comprises one Ig-like V-type domain and two Ig-like C2-type domains in the extracellular region. The V domain is believed to mediate nectin binding to its ligands. Nectin2 is known to bind the pseudorabies virus, and herpes simplex virus2 (HSV2), involving in cell to cell spreading of these viruses. It does not bind poliovirus. As a homophilic adhesion molecule, CD112 is found concentrated in adherens junctions, and exists on neurons, endothelial cells,epithelial cells and fibroblasts. CD112 has been identified as the ligand for DNAM-1 (CD226), and the interaction of CD226/CD112 mediates cytotoxicity and cytokine secretion by T and NK cells. The costimulatory responses may be a critical component in allergic reactions and may therefore become targets for anti-allergic therapy.
Alternative Names: Poliovirus Receptor-Related Protein 2, Herpes Virus Entry Mediator B, Herpesvirus Entry Mediator B, HveB, Nectin-2, CD112, PVRL2, HVEB, PRR2 - 分子量
- 36.58 kDa
- UniProt
- Q92692
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization
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