GNMT Protein (AA 2-294) (His tag)
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- 抗原 See all GNMT 蛋白
- GNMT (Glycine N-Methyltransferase (GNMT))
- 蛋白类型
- Recombinant
- 产品特性
- AA 2-294
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This GNMT protein is labelled with His tag.
- 原理
- Recombinant Human Glycine N-Methyltransferase/GNMT (N-6His)
- 序列
- MGSSHHHHHH SSGLVPRGSH MVDSVYRTRS LGVAAEGLPD QYADGEAARV WQLYIGDTRS RTAEYKAWLL GLLRQHGCQR VLDVACGTGV DSIMLVEEGF SVTSVDASDK MLKYALKERW NRRHEPAFDK WVIEEANWMT LDKDVPQSAE GGFDAVICLG NSFAHLPDCK GDQSEHRLAL KNIASMVRAG GLLVIDHRNY DHILSTGCAP PGKNIYYKSD LTKDVTTSVL IVNNKAHMVT LDYTVQVPGA GQDGSPGLSK FRLSYYPHCL ASFTELLQAA FGGKCQHSVL GDFKPYKPGQ TYIPCYFIHV LKRTD
- 产品特性
- Recombinant Human Glycine N-Methyltransferase/GNMT is produced by our E. coli expression system. The target protein is expressed with sequence (Val2-Asg294) of Human GNMT fused with a 6His tag at the N-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product GNMT 蛋白
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Glycine N-Methyltransferase (GNMT) (AA 1-295) protein (His tag)
GNMT 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % by SDS - PAGE SDS
Glycine N-Methyltransferase (GNMT) (AA 1-100) protein (GST tag)GNMT 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Glycine N-Methyltransferase (GNMT) (AA 1-295) protein (GST tag)GNMT 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Glycine N-Methyltransferase (GNMT) (AA 2-295) protein (His tag)Crystallography grade GNMT 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Glycine N-Methyltransferase (GNMT) (AA 2-293) protein (His tag)Crystallography grade GNMT 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Glycine N-Methyltransferase (GNMT) (AA 1-295) (Active) protein (His tag)GNMT 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % by SDS - PAGE SDS Active
Glycine N-Methyltransferase (GNMT) protein (Myc-DYKDDDDK Tag)GNMT 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- -80 °C
- 储存方法
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - 有效期
- 6 months
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- 抗原
- GNMT (Glycine N-Methyltransferase (GNMT))
- 别名
- Glycine-N-methyltransferase (GNMT 产品)
- 别名
- glycine N-methyltransferase Protein, CpipJ_CPIJ015956 Protein, Gnmt Protein, GNMT Protein
- Sub Type
- Fusionprotein
- 背景
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Glycine N-Methyltransferase (GNMT) is a tetrameric cytosolic protein. GNMT catalyzes the synthesis of N-methylglycine from glycine using S-adenosylmethionine (AdoMet) as the methyl donor. It can affects DNA methylation by regulating the ratio of S-adenosylmethionine to S-adenosylhomocystine, playing an important role in maintaining normal AdoMet levels. GNMT is highly expressed in liver. As a major folate-binding protein, GNMT takes part in the detoxification pathway. Defects in GNMT are the cause of hypermethioninemia. the patients with this deficiency are mild hepatomegaly and chronic elevation of serum transaminases.
Alternative Names: Glycine N-Methyltransferase, GNMT - 分子量
- 34.9 kDa
- UniProt
- Q14749
- 途径
- Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process
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