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GNMT Protein (His tag)

GNMT 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7318543
发货至: 中国
  • 抗原 See all GNMT 蛋白
    GNMT (Glycine N-Methyltransferase (GNMT))
    蛋白类型
    Recombinant
    宿主
    • 10
    • 1
    • 1
    • 1
    资源
    • 6
    • 2
    • 2
    • 2
    • 1
    大肠杆菌(E. Coli)
    标记
    This GNMT protein is labelled with His tag.
    原理
    Recombinant Human GNMT Protein (His Tag)
    序列
    Met 1-Asg294
    产品特性
    Recombinant Human Glycine N-Methyltransferase is produced by our E.coli expression system and the target gene encoding Met1-Asg294 is expressed with a 6His tag at the N-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product GNMT 蛋白
  • 限制
    仅限研究用
  • 状态
    Frozen, Liquid
    缓冲液
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.
    储存条件
    -20 °C
    储存方法
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • 抗原
    GNMT (Glycine N-Methyltransferase (GNMT))
    别名
    GNMT (GNMT 产品)
    别名
    glycine N-methyltransferase Protein, CpipJ_CPIJ015956 Protein, Gnmt Protein, GNMT Protein
    背景

    Background: Glycine N-Methyltransferase (GNMT) is a tetrameric cytosolic protein. GNMT catalyzes the synthesis of N-methylglycine from glycine using S-adenosylmethionine (AdoMet) as the methyl donor. It can affects DNA methylation by regulating the ratio of S-adenosylmethionine to S-adenosylhomocystine, playing an important role in maintaining normal AdoMet levels. GNMT is highly expressed in liver. As a major folate-binding protein, GNMT takes part in the detoxification pathway. Defects in GNMT are the cause of hypermethioninemia. the patients with this deficiency are mild hepatomegaly and chronic elevation of serum transaminases.

    Synonym: Glycine N-Methyltransferase, GNMT

    分子量
    34.9 kDa
    UniProt
    Q14749
    途径
    Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process
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