GNMT Protein (AA 1-295) (His tag)
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北京 101111
Quick Overview for GNMT Protein (AA 1-295) (His tag) (ABIN7318543)
抗原
See all GNMT 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 1-295
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标记
- This GNMT protein is labelled with His tag.
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原理
- Recombinant Human GNMT Protein (His Tag)
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序列
- Met1-Asp295
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产品特性
- Recombinant Human Glycine N-Methyltransferase is produced by our E.coli expression system and the target gene encoding Met1-Asg294 is expressed with a 6His tag at the N-terminus.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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Glycine N-Methyltransferase (GNMT) (AA 1-295) protein (GST tag)
GNMT 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Glycine N-Methyltransferase (GNMT) (AA 1-295) (Active) protein (His tag)GNMT 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % SDS, EAA Active
Glycine N-Methyltransferase (GNMT) protein (Myc-DYKDDDDK Tag)GNMT 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, pH 8.0.
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储存条件
- -20 °C
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储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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有效期
- 6 months
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- GNMT (Glycine N-Methyltransferase (GNMT))
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别名
- GNMT
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背景
- GNMT,Glycine N-Methyltransferase,Glycine N-Methyltransferase (GNMT) is a tetrameric cytosolic protein. GNMT catalyzes the synthesis of N-methylglycine from glycine using S-adenosylmethionine (AdoMet) as the methyl donor. It can affects DNA methylation by regulating the ratio of S-adenosylmethionine to S-adenosylhomocystine, playing an important role in maintaining normal AdoMet levels. GNMT is highly expressed in liver. As a major folate-binding protein, GNMT takes part in the detoxification pathway. Defects in GNMT are the cause of hypermethioninemia. the patients with this deficiency are mild hepatomegaly and chronic elevation of serum transaminases.
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分子量
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Calculated MW: 34.9 kDa
Observed MW: 33-37 kDa
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基因ID
- 27232
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UniProt
- Q14749
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途径
- Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process
抗原
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