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CD3 epsilon Protein (CD3E) (AA 23-126) (His tag)

CD3E 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN1096311
发货至: 中国
  • 抗原 See all CD3 epsilon (CD3E) 蛋白
    CD3 epsilon (CD3E)
    蛋白类型
    Recombinant
    产品特性
    AA 23-126
    宿主
    • 24
    • 9
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    资源
    • 23
    • 8
    • 5
    • 4
    • 2
    • 2
    人细胞
    标记
    This CD3 epsilon protein is labelled with His tag.
    原理
    Recombinant Human CD3 ε/CD3E (C-6His)
    序列
    DGNEEMGGIT QTPYKVSISG TTVILTCPQY PGSEILWQHN DKNIGGDEDD KNIGSDEDHL SLKEFSELEQ SGYYVCYPRG SKPEDANFYL YLRARVCENC MEMDVDHHHH HH
    产品特性
    Recombinant Human T-Cell Surface Glycoprotein CD3 epsilon Chain/CD3epsilon is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Asp23-Asp126) of Human CD3epsilon fused with a polyhistidine tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    过滤
    0.2 μm filtered
    内毒素水平
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product CD3E 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
    注意事项
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    储存条件
    4 °C/-20 °C/-80 °C
    储存方法
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    3 months
  • 抗原
    CD3 epsilon (CD3E)
    别名
    cd3-epsilon (CD3E 产品)
    别名
    cd3e Protein, CD3E Protein, t3e Protein, tcre Protein, AI504783 Protein, CD3 Protein, CD3epsilon Protein, T3e Protein, T3E Protein, TCRE Protein, CD3e molecule Protein, CD3 antigen, epsilon polypeptide Protein, cd3e Protein, CD3E Protein, Cd3e Protein
    Sub Type
    Fusionprotein
    背景
    T-Cell Surface Glycoprotein CD3 epsilon Chain (CD3epsilon) is a single-pass type I membrane protein. CD3epsilon contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain. CD3epsilon is a polypeptide encoded by the CD3E gene on chromosome 11 in humans. The T cell receptor-CD3 complex (TCR/CD3 complex) is involved in T-cell development and several intracellular signal-transduction pathways. This complex is critical for T-cell development and function, and represents one of the most complex transmembrane receptors. The T cell receptor-CD3 complex is unique in having ten cytoplasmic immunoreceptor tyrosine-based activation motifs (ITAMs). TCR/CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.
    Alternative Names: T-Cell Surface Glycoprotein CD3 Epsilon Chain, T-Cell Surface Antigen T3/Leu-4 Epsilon Chain, CD3e, CD3E, T3E
    分子量
    12.79 kDa
    UniProt
    P07766
    途径
    TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
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