电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

ABL1 Protein (AA 4-194, partial) (GST tag)

ABL1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant 90 % ELISA
产品编号 ABIN1047855
发货至: 中国
  • 抗原 See all ABL1 蛋白
    ABL1 (C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1))
    蛋白类型
    Recombinant
    产品特性
    AA 4-194, partial
    宿主
    • 17
    • 4
    • 1
    资源
    • 9
    • 4
    • 4
    • 3
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This ABL1 protein is labelled with GST tag.
    应用范围
    ELISA
    序列
    ICLKLVGCKS KKGLSSSSSC YLEEALQRPV ASDFEPQGLS EAARWNSKEN LLAGPSENDP NLFVALYDFV ASGDNTLSIT KGEKLRVLGY NHNGEWCEAQ TKNGQGWVPS NYITPVNSLE KHSWYHGPVS RNAAEYLLSS GINGSFLVRE SESSPGQRSI SLRYEGRVYH YRINTASDGK LYVSSESRFN T
    产品特性
    Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.
    纯度
    90 %
    Top Product
    Discover our top product ABL1 蛋白
  • 说明

    The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

    限制
    仅限研究用
  • 状态
    Lyophilized
    浓度
    0.2-2 mg/mL
    缓冲液
    Tris-based buffer, 50 % glycerol
    注意事项
    Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week
    储存条件
    -20 °C
    储存方法
    Store at -20 °C for extended storage, conserve at -20 °C or -80 °C
  • Fainstein, Einat, Gokkel, Marcelle, Croce, Gale, Canaani: "Nucleotide sequence analysis of human abl and bcr-abl cDNAs." in: Oncogene, Vol. 4, Issue 12, pp. 1477-81, (1990) (PubMed).

    Shtivelman, Lifshitz, Gale, Roe, Canaani: "Alternative splicing of RNAs transcribed from the human abl gene and from the bcr-abl fused gene." in: Cell, Vol. 47, Issue 2, pp. 277-84, (1986) (PubMed).

  • 抗原
    ABL1 (C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1))
    别名
    Tyrosine-Protein Kinase ABL1 Protein (ABL1 产品)
    别名
    ABL Protein, JTK7 Protein, bcr/abl Protein, c-ABL Protein, p150 Protein, v-abl Protein, AI325092 Protein, Abl Protein, E430008G22Rik Protein, c-Abl Protein, ABL proto-oncogene 1, non-receptor tyrosine kinase Protein, c-abl oncogene 1, non-receptor tyrosine kinase Protein, Tyrosine-protein kinase abl-1 Protein, ABL1 Protein, Abl1 Protein, abl-1 Protein, abl1 Protein
    背景
    Protein kinase that regulates key processes linked to cell growth and survival. Regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics. Regulates DNA repair potentially by activating the proapoptotic pathway when the DNA damage is too severe to be repaired. Phosphorylates PSMA7 that leads to an inhibition of proteasomal activity and cell cycle transition blocks.
    分子量
    48.5 kD
    UniProt
    P00520
    途径
    Apoptosis, Regulation of Muscle Cell Differentiation, Platelet-derived growth Factor Receptor Signaling, Lipid Metabolism
You are here:
客服