TNFSF15 蛋白

蛋白简介

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Two transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with TNFSF15

• tumor necrosis factor superfamily member 15 (TNFSF15) 抗体
• TNF superfamily member 15 (TNFSF15) 抗体
• tumor necrosis factor (ligand) superfamily, member 15 (Tnfsf15) 抗体
• TNF superfamily member 15 (Tnfsf15) 抗体

• Tl1 抗体
• Tl1a 抗体
• TTPAL 抗体
• Vegi 抗体
• VEGI192A 抗体

Protein level used designations for TNFSF15

tumor necrosis factor ligand superfamily member 15 , vascular endothelial growth inhibitor , tocopherol (alpha) transfer protein-like , TNF ligand-related molecule 1 , TNF superfamily ligand TL1A , vascular endothelial cell growth inhibitor , vascular endothelial growth inhibitor-192A , bM20K13.3 (tumor necrosis factor (ligand) superfamily, member 15)