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PDK2 抗体

(Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2))
This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010].
PDK2 抗体  (AA 187-276) PDK2 抗体  (AA 187-276) PDK2 抗体 (AA 187-276) (ABIN562160)

PDK2 适用: 人 WB, ELISA, IHC (p), RNAi 宿主: 小鼠 Monoclonal 2G1 unconjugated

PDK2 抗体  (AA 155-379) PDK2 抗体  (AA 155-379) PDK2 抗体 (AA 155-379) (ABIN7439423)

PDK2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

PDK2 抗体  (AA 178-404) PDK2 抗体  (AA 178-404) PDK2 抗体 (AA 178-404) (ABIN5542665)

PDK2 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 3F2D7 unconjugated

PDK2 抗体 by 适用

Find PDK2 抗体 for a variety of species such as anti-Human PDK2, anti-Mouse PDK2, anti-Rat PDK2. The species listed below are among those available. Click on a link to go to the corresponding products.

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Find PDK2 抗体 validated for a specific application such as WB, ELISA, IHC, IHC (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

PDK2 抗体 by 抗体来源

Find PDK2 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

PDK2 抗体 by 抗原表位

Find PDK2 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

PDK2 抗体 by 克隆形成能力

Find available monoclonal or polyclonal PDK2 抗体. Click on a link to go to the corresponding products.

PDK2 抗体 by 克隆

Find PDK2 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

PDK2 抗体 by 标记

Find PDK2 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular PDK2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), RNAi
Validations
  • (4)
  • (6)
Cat. No. ABIN562160
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (6)
Cat. No. ABIN7439423
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, FACS
Validations
  • (5)
Cat. No. ABIN5542665
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p), ICC
Validations
  • (6)
Cat. No. ABIN3032416
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Monkey, Mouse, Primate, Rat
Application WB, ELISA, IHC (p)
Validations
  • (4)
  • (3)
Cat. No. ABIN545486
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (4)
Cat. No. ABIN1681304
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7142006
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Rat
Application WB, IHC (p), ICC
Validations
  • (4)
Cat. No. ABIN3044044
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (4)
Cat. No. ABIN657996
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), FACS
Validations
  • (4)
  • (3)
Cat. No. ABIN653784
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (10)
  • (2)
Cat. No. ABIN391037
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (2)
Cat. No. ABIN4912898
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN562159
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN518757
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow, Human
Application WB, IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN6746981
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our PDK2 抗体

Hu, Yu, Li, Ren, Ning, Wang, Liang, Li: "PDK2 induces cisplatin-resistance in lung adenocarcinoma via transcriptional regulation of CNNM3." in: Journal of drug targeting, Vol. 27, Issue 4, pp. 460-465, (2019) (PubMed).

Qvit, Disatnik, Sho, Mochly-Rosen: "Selective Phosphorylation Inhibitor of Delta Protein Kinase C-Pyruvate Dehydrogenase Kinase Protein-Protein Interactions: Application for Myocardial Injury in Vivo." in: Journal of the American Chemical Society, Vol. 138, Issue 24, pp. 7626-35, (2018) (PubMed).

Qvit, Joshi, Cunningham, Ferreira, Mochly-Rosen: "Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Protein-Protein Interaction Inhibitor Reveals a Non-catalytic Role for GAPDH Oligomerization in Cell Death." in: The Journal of biological chemistry, Vol. 291, Issue 26, pp. 13608-21, (2016) (PubMed).

Le Page, Rider, Lewis, Ball, Clarke, Johansson, Carr, Heather, Tyler: "Increasing Pyruvate Dehydrogenase Flux as a Treatment for Diabetic Cardiomyopathy: A Combined 13C Hyperpolarized Magnetic Resonance and Echocardiography Study." in: Diabetes, Vol. 64, Issue 8, pp. 2735-43, (2015) (PubMed).

Hou, Zhang, Han, Ge, Ma, Zhang, Moley, Schedl, Wang: "Differing roles of pyruvate dehydrogenase kinases during mouse oocyte maturation." in: Journal of cell science, Vol. 128, Issue 13, pp. 2319-29, (2015) (PubMed).

Hurd, Collins, Abakumova, Chouchani, Baranowski, Fearnley, Prime, Murphy, James: "Inactivation of pyruvate dehydrogenase kinase 2 by mitochondrial reactive oxygen species." in: The Journal of biological chemistry, Vol. 287, Issue 42, pp. 35153-60, (2012) (PubMed).

Yamasaki, Kawabe, Nakamura, Tachibana, Ishimoto, Tanaka, Aburatani, Sakai, Hamakubo, Kodama, Doi: "Fenofibrate suppresses growth of the human hepatocellular carcinoma cell via PPAR?-independent mechanisms." in: European journal of cell biology, Vol. 90, Issue 8, pp. 657-64, (2011) (PubMed).

Love, LeBlanc, Inglis, Bradley, Choptiany, Heigenhauser, Peters: "The relationship between human skeletal muscle pyruvate dehydrogenase phosphatase activity and muscle aerobic capacity." in: Journal of applied physiology (Bethesda, Md. : 1985), Vol. 111, Issue 2, pp. 427-34, (2011) (PubMed).

Dunford, Herbst, Jeoung, Gittings, Inglis, Vandenboom, LeBlanc, Harris, Peters: "PDH activation during in vitro muscle contractions in PDH kinase 2 knockout mice: effect of PDH kinase 1 compensation." in: American journal of physiology. Regulatory, integrative and comparative physiology, Vol. 300, Issue 6, pp. R1487-93, (2011) (PubMed).

Sun, Chang, Fu, Liu, Califano: "Chronic CSE treatment induces the growth of normal oral keratinocytes via PDK2 upregulation, increased glycolysis and HIF1? stabilization." in: PLoS ONE, Vol. 6, Issue 1, pp. e16207, (2011) (PubMed).

Aliases for PDK2 抗体

pyruvate dehydrogenase kinase 2 (PDK2) 抗体
pyruvate dehydrogenase kinase, isoenzyme 2 (Pdk2) 抗体
pyruvate dehydrogenase kinase 2 (Pdk2) 抗体
pyruvate dehydrogenase kinase, isozyme 2b (pdk2b) 抗体
PDHK2 抗体
Pdk 抗体
PDK2 抗体
PDKII 抗体
zgc:56209 抗体
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