PDLIM2 抗体
(PDZ and LIM Domain 2 (PDLIM2))
This gene encodes a member of the ALP subfamily of PDZ-LIM domain proteins. The encoded protein suppresses anchorage-dependent growth and promotes cell migration and adhesion through interactions with the actin cytoskeleton via the PDZ domain. The encoded protein is also a putative tumor suppressor protein, and decreased expression of this gene is associated with several malignancies including breast cancer and adult T-cell leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011].
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Latest Publications for our PDLIM2 抗体
: "Human T-cell leukemia virus type 1 bZIP factor selectively suppresses the classical pathway of NF-kappaB." in: Blood, Vol. 113, Issue 12, pp. 2755-64, (2009) (PubMed).
: "Role of T-loop phosphorylation in PDK1 activation, stability, and substrate binding." in: The Journal of biological chemistry, Vol. 280, Issue 19, pp. 18797-802, (2005) (PubMed).
: "Mouse 3-phosphoinositide-dependent protein kinase-1 undergoes dimerization and trans-phosphorylation in the activation loop." in: The Journal of biological chemistry, Vol. 278, Issue 44, pp. 42913-9, (2003) (PubMed).
: "Role of T-loop phosphorylation in PDK1 activation, stability, and substrate binding." in: The Journal of biological chemistry, Vol. 280, Issue 19, pp. 18797-802, (2005) (PubMed).
: "Mouse 3-phosphoinositide-dependent protein kinase-1 undergoes dimerization and trans-phosphorylation in the activation loop." in: The Journal of biological chemistry, Vol. 278, Issue 44, pp. 42913-9, (2003) (PubMed).
Aliases for PDLIM2 抗体
PDZ and LIM domain 2 (Pdlim2) 抗体PDZ and LIM domain 2 (PDLIM2) 抗体
4732462F18Rik 抗体
MYSTIQUE 抗体
Slim 抗体
SLIM 抗体
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