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PDK2 抗体

PDK2 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB23089 unconjugated
产品编号 ABIN653784
发货至: 中国
  • 抗原 See all PDK2 抗体
    PDK2 (Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2))
    适用
    • 90
    • 54
    • 46
    • 10
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 84
    • 13
    克隆类型
    • 77
    • 20
    多克隆
    标记
    • 44
    • 8
    • 6
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    This PDK2 antibody is un-conjugated
    应用范围
    • 81
    • 49
    • 39
    • 17
    • 14
    • 13
    • 8
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This PDK2 antibody is generated from rabbits immunized with recombinant protein of human PDK2.
    克隆位点
    RB23089
    亚型
    Ig Fraction
    Top Product
    Discover our top product PDK2 Primary Antibody
  • 应用备注
    WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Qvit, Disatnik, Sho, Mochly-Rosen: "Selective Phosphorylation Inhibitor of Delta Protein Kinase C-Pyruvate Dehydrogenase Kinase Protein-Protein Interactions: Application for Myocardial Injury in Vivo." in: Journal of the American Chemical Society, Vol. 138, Issue 24, pp. 7626-35, (2018) (PubMed).

    Qvit, Joshi, Cunningham, Ferreira, Mochly-Rosen: "Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Protein-Protein Interaction Inhibitor Reveals a Non-catalytic Role for GAPDH Oligomerization in Cell Death." in: The Journal of biological chemistry, Vol. 291, Issue 26, pp. 13608-21, (2016) (PubMed).

    Le Page, Rider, Lewis, Ball, Clarke, Johansson, Carr, Heather, Tyler: "Increasing Pyruvate Dehydrogenase Flux as a Treatment for Diabetic Cardiomyopathy: A Combined 13C Hyperpolarized Magnetic Resonance and Echocardiography Study." in: Diabetes, Vol. 64, Issue 8, pp. 2735-43, (2015) (PubMed).

    Sun, Chang, Fu, Liu, Califano: "Chronic CSE treatment induces the growth of normal oral keratinocytes via PDK2 upregulation, increased glycolysis and HIF1? stabilization." in: PLoS ONE, Vol. 6, Issue 1, pp. e16207, (2011) (PubMed).

  • 抗原
    PDK2 (Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2))
    别名
    PDK2 (PDK2 产品)
    别名
    PDHK2 antibody, PDKII antibody, Pdk antibody, zgc:56209 antibody, PDK2 antibody, pyruvate dehydrogenase kinase 2 antibody, pyruvate dehydrogenase kinase, isoenzyme 2 antibody, pyruvate dehydrogenase kinase, isozyme 2b antibody, PDK2 antibody, Pdk2 antibody, pdk2b antibody
    背景
    PDK2 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.
    分子量
    46154
    基因ID
    5164
    NCBI登录号
    NP_001186827, NP_001186828, NP_002602
    UniProt
    Q15119
    途径
    PI3K-Akt Signaling, RTK signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect
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