anti-人 SQSTM1 抗体 for Immunofluorescence (Paraffin-embedded Sections)

Recommended SQSTM1 Antibody (supplied by: Log in to see )

抗原
Sequestosome 1 (SQSTM1) 抗体
  • SQSTM1
  • sqstm1
  • MGC79491
  • A170
  • OSIL
  • PDB3
  • ZIP3
  • p60
  • p62
  • p62B
  • OSF-6
  • Osi
  • STAP
  • ZIP
  • sb:cb621
  • zgc:85784
  • sequestosome 1
  • sequestosome 1 L homeolog
  • SQSTM1
  • sqstm1
  • Sqstm1
  • sqstm1.L
抗原表位
AA 80-130
68
41
36
36
25
19
19
16
14
14
12
12
11
9
8
8
8
6
5
5
4
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
适用
人, 小鼠, 大鼠
377
198
126
8
5
5
5
4
4
4
2
2
2
2
2
1
1
1
1
宿主

299
69
6
3
克隆类型
多克隆
标记
This SQSTM1 antibody is un-conjugated
20
18
17
13
13
12
6
6
5
5
5
5
5
5
4
4
4
4
4
4
4
4
4
4
4
2
2
2
1
1
1
1
1
1
1
1
1
1
1
应用范围
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
309
132
115
91
82
69
51
38
35
28
18
12
4
3
2
选项
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产品编号 ABIN682153
$ 318.45
加上运输费 $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN916350 IF (p) Alexa Fluor 555 Rabbit IgG AA 80-130 Log in to see Polyclonal 0
1 ABIN916349 IF (p) Alexa Fluor 488 Rabbit IgG AA 80-130 Log in to see Polyclonal 0
1 ABIN916348 IF (p) Alexa Fluor 350 Rabbit IgG AA 80-130 Log in to see Polyclonal 0
1 ABIN916351 IF (p) Alexa Fluor 647 Rabbit IgG AA 80-130 Log in to see Polyclonal 0
1 ABIN682156 IF (p) Cy3 Rabbit IgG AA 80-130 Log in to see Polyclonal 0
1 ABIN682157 IF (p) Cy5 Rabbit IgG AA 80-130 Log in to see Polyclonal 0
1 ABIN682158 IF (p) Cy5.5 Rabbit IgG AA 80-130 Log in to see Polyclonal 0
1 ABIN682159 IF (p) Cy7 Rabbit IgG AA 80-130 Log in to see Polyclonal 0
1 ABIN682160 IF (p) FITC Rabbit IgG AA 80-130 Log in to see Polyclonal 0
1 ABIN2806648 IF (p) Alexa Fluor 594 Rabbit IgG AA 80-130 Log in to see Polyclonal 0
1 ABIN5010967 IF (p) Alexa Fluor 680 Rabbit IgG AA 80-130 Log in to see Polyclonal 0
1 ABIN5010968 IF (p) Alexa Fluor 750 Rabbit IgG AA 80-130 Log in to see Polyclonal 0

General

抗原 Sequestosome 1 (SQSTM1) 抗体
抗原表位 AA 80-130
(68), (41), (36), (36), (25), (19), (19), (16), (14), (14), (12), (12), (11), (9), (8), (8), (8), (6), (5), (5), (4), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
适用 人, 小鼠, 大鼠
(377), (198), (126), (8), (5), (5), (5), (4), (4), (4), (2), (2), (2), (2), (2), (1), (1), (1), (1)
宿主
(299), (69), (6), (3)
克隆类型
多克隆
标记 This SQSTM1 antibody is un-conjugated
(20), (18), (17), (13), (13), (12), (6), (6), (5), (5), (5), (5), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
应用范围 Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(309), (132), (115), (91), (82), (69), (51), (38), (35), (28), (18), (12), (4), (3), (2)
Pubmed 4个引用可参考
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SQSTM1抗体详情

SQSTM1目标详情 使用细节 贮存及处理 References for anti-SQSTM1 antibody (ABIN682153) 图像
纯化方法 Purified by Protein A.
免疫原 KLH conjugated synthetic peptide derived from human SQSTM1/Ubiquitin-binding protein p62
亚型 IgG
Plasmids, Primers & others

SQSTM1目标详情

SQSTM1抗体详情 使用细节 贮存及处理 References for anti-SQSTM1 antibody (ABIN682153) 图像 回页首
抗原
别名 Sqstm1 (SQSTM1 Antibody 摘要)
背景

Autophagy receptor that interacts directly with both the cargo to become degraded and an autophagy modifier of the MAP1 LC3 family. Required both for the formation and autophagic degradation of polyubiquitin-containing bodies, called ALIS (aggresome-like induced structures) and links ALIS to the autophagic machinery. Involved in midbody ring degradation. May regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. May play a role in titin/TTN downstream signaling in muscle cells. May regulate signaling cascades through ubiquitination. Adapter that mediates the interaction between TRAF6 and CYLD (By similarity). May be involved in cell differentiation, apoptosis, immune response and regulation of K(+) channels.

Subcellular location: Cytoplasm, Nucleus

Synonyms: p60, p62, A170, OSIL, PDB3, ZIP3, p62B, Sequestosome-1, EBI3-associated protein of 60 kDa, EBIAP, Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa, Ubiquitin-binding protein p62, SQSTM1, ORCA

基因ID 8878
UniProt Q13501
途径 NF-kappaB Signaling, Neurotrophin Signaling Pathway, Autophagy

使用细节

SQSTM1抗体详情 SQSTM1目标详情 贮存及处理 References for anti-SQSTM1 antibody (ABIN682153) 图像 回页首
应用备注 WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
限制 仅限研究用

贮存及处理

SQSTM1抗体详情 SQSTM1目标详情 使用细节 References for anti-SQSTM1 antibody (ABIN682153) 图像 回页首
状态 Liquid
浓度 1 μg/μL
缓冲液 Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
储存条件 -20 °C
储存方法 Store at -20°C
有效期 12 months

References for anti-SQSTM1 antibody (ABIN682153)

SQSTM1抗体详情 SQSTM1目标详情 使用细节 贮存及处理 图像 回页首
有引用在:

Kuo, Weng, Chang, Huang, Lin, Chuang, Lin, Liou, Tai, Lin, Wang: "Altered mitochondrial dynamics and response to insulin in cybrid cells harboring a diabetes-susceptible mitochondrial DNA haplogroup." in: Free radical biology & medicine, Vol. 96, pp. 116-29, 2016 Method employed by authors: Western Blotting (WB) (Sample species: Human).

Xia, Gao, Zhang, Wang, Zhao, Che, Ao, Yang, Wang, Lei: "Autophagy mediated by arginine depletion activation of the nutrient sensor GCN2 contributes to interferon-γ-induced malignant transformation of primary bovine mammary epithelial cells." in: Cell death discovery, Vol. 2, pp. 15065, 2016 Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Cow (Bovine)). Further details: Sample: mammary gland

Cui, Luo, Li, Li, Wang: "Changes of intracellular Ca2+ in quercetin-induced autophagy progression." in: Acta biochimica et biophysica Sinica, Vol. 47, Issue 11, pp. 908-14, 2015 Method employed by authors: Western Blotting (WB) (Sample species: Human).

Chen, Wei, Nie, Lin, Tian, Liu, Yu, Cheng, Yan, Wang, Liu, Deng, Lai, Zhou, Zhang, Lin, Chen: "?-Asarone prevents autophagy and synaptic loss by reducing ROCK expression in asenescence-accelerated prone 8 mice." in: Brain research, Vol. 1552, pp. 41-54, 2014 Method employed by authors: Western Blotting (WB) (Sample species: Mouse (Murine)). Further details: Sample: brain

图像

SQSTM1抗体详情 SQSTM1目标详情 使用细节 贮存及处理 References for anti-SQSTM1 antibody (ABIN682153) 回页首
厂商提供的图像
ELISA image for anti-Sequestosome 1 (SQSTM1) (AA 80-130) antibody (ABIN682153) 0.2 µg/100 µL Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:3...
Immunohistochemistry (IHC) image for anti-Sequestosome 1 (SQSTM1) (AA 80-130) antibody (ABIN682153) Formalin-fixed and paraffin embedded rat brain labeled with Anti-SQSTM1 Polyclonal An...
SDS-PAGE (SDS) image for anti-Sequestosome 1 (SQSTM1) (AA 80-130) antibody (ABIN682153) L1 rat kidney lysates, L2 rat brain lysates probed : Anti-GDF9 (ABIN682153) at 1:200 ...
Western Blotting (WB) image for anti-Sequestosome 1 (SQSTM1) (AA 80-130) antibody (ABIN682153) HeLa cell lysates probed with Anti-SQSTM1 Polyclonal Antibody, Unconjugated at 1:500...
Western Blotting (WB) image for anti-Sequestosome 1 (SQSTM1) (AA 80-130) antibody (ABIN682153) L1 rat kidney lysates, L2 rat brain lysates probed : Anti-GDF9 at 1:200 in 4˚C. Foll...