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Human Polyclonal ATF3 Primary Antibody for IF (p), IHC (p) - ABIN669561
Hu, Li, Li: MARVELD1 Inhibits Nonsense-Mediated RNA Decay by Repressing Serine Phosphorylation of UPF1. in PLoS ONE 2013
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Human Polyclonal ATF3 Primary Antibody for ICC, IF - ABIN4282009
Wu, Nguyen, Dziunycz, Chang, Brooks, Lefort, Hofbauer, Dotto: Opposing roles for calcineurin and ATF3 in squamous skin cancer. in Nature 2010
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Human Monoclonal ATF3 Primary Antibody for RNAi, ELISA - ABIN559974
Chen, Huang, Chu, Chen, Chou, Wang, Kulp, Teng, Wang, Chen: Energy restriction-mimetic agents induce apoptosis in prostate cancer cells in part through epigenetic activation of KLF6 tumor suppressor gene expression. in The Journal of biological chemistry 2011
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Human Polyclonal ATF3 Primary Antibody for IHC (p), IHC - ABIN315461
Maciag, Nandurdikar, Hong, Chakrapani, Diwan, Morris, Shami, Shiao, Anderson, Keefer, Saavedra: Activation of the c-Jun N-terminal kinase/activating transcription factor 3 (ATF3) pathway characterizes effective arylated diazeniumdiolate-based nitric oxide-releasing anticancer prodrugs. in Journal of medicinal chemistry 2011
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Human Monoclonal ATF3 Primary Antibody for ELISA, WB - ABIN559976
Hsueh, Kuo, Chen: Transcriptional regulators of the ?Np63: their role in limbal epithelial cell proliferation. in Journal of cellular physiology 2012
Human Polyclonal ATF3 Primary Antibody for FACS, WB - ABIN1536715
Mo, Dai, Kang, Cui, He et al.: Ectopic expression of human MutS homologue 2 on renal carcinoma cells is induced by oxidative stress with interleukin-18 promotion via p38 mitogen-activated protein kinase (MAPK) and c-Jun N-terminal ... in The Journal of biological chemistry 2012
Data show that Atf3 was detected in retinal ganglion cell axons in both the nerve fiber layer and the optic nerve on the injured side.
Data show that ATF3 may be an important mediator of optic nerve regeneration-promoting gene expression in fish, a role which merits further investigation.
Data show that amino acid limitation (amino acid response, AAR) activation of activating transcription factor 3 (ATF3) transcription is transient relative to activation by the unfolded protein response (UPR).
In patients with NAFLD (显示 TSC2 抗体) and/or T2D, a significant positive correlation was observed between hepatic ATF3 expression and surrogate markers of T2D, mitochondrial dysfunction, and macrophage infiltration.
our results suggest that ATF3 promotes the invasion and proliferation of CRC (显示 CALR 抗体) cells, at least in part, via the regulation of CEACAM1 (显示 CEACAM1 抗体)-mediated EMT (显示 ITK 抗体).
ATF3 is involved in promoting particulate matter-induced pulmonary inflammation.
Negative pressure wound therapy exerts an anti-inflammatory effect, possibly through the suppression of proinflammatory enzymes and cytokines resulting from Ik B-alpha inhibition and ATF-3 activation, which may prevent the activation of the NF-kappaB (显示 NFKB1 抗体) pathway in human diabetic foot wounds.
ATF3 plays a significant role in regulating human endometrial receptivity and embryo attachment in vitro via up-regulation of leukemia inhibitory factor (显示 LIF 抗体).
Upregulation of ATF3 in lung cancer promotes cell proliferation, migration, and invasion, and may represent a novel therapeutic target for lung cancer
ATF3 is a negative regulator of inflammation in human fetal membranes; in primary amnion cells, ATF3 expression is induced by IL-1beta (显示 IL1B 抗体) and fsl-1 (显示 FSTL1 抗体), and ATF3 silencing further exacerbates the inflammatory response when stimulated with these factors. Subsequently, ATF3 expression is decreased in fetal membranes after term labour and with preterm chorioamnionitis, conditions closely associated with inflammation and infection.
Altering TR4 (显示 NR2C2 抗体)-ATF3 signaling increases the efficacy of cisplatin to suppress hepatocellular carcinoma growth/progression.
ATF3 may be a potential early diagnostic biomarker for silicosis and ATF3 acts as a repressor in inflammatory responses induced by silica
Conditional deletion of ATF3 in osteoclast precursors protects RANKL (显示 TNFSF11 抗体)-induced osteoclast activation and bone loss.
Data (including data from studies using mutant, transgenic, and knockout mice) suggest that gene targets of leptin/leptin (显示 LEP 抗体)-receptor (显示 LEPR 抗体) (Lep (显示 LEP 抗体)/Lepr (显示 LEPR 抗体)) signaling in hypothalamic neurons regulate energy metabolism; Lep (显示 LEP 抗体)/Lepr (显示 LEPR 抗体) signaling appears to up-regulate expression of Atf3 (activating transcription factor-3) in hypothalamic neurons.
ATF3 promotes macrophage migration and reverses M1polarized macrophages to the M2 phenotype by upregulation of TNC via the Wnt/betacatenin signaling pathway.
Microglia make contact through unknown neuronal signals regulated by ATF3 in hypoglossal nucleus.
ATF3 inhibit the expression and release of TNF-alpha (显示 TNF 抗体), IL-1beta (显示 IL1B 抗体), IL-6 (显示 IL6 抗体), and IL-18 (显示 IL18 抗体) induced by Mycoplasma pneumonia in vitro and in vivo, which is associated with its negative regulation of Egr-1 (显示 EGR1 抗体)/Fyn (显示 FYN 抗体) signaling pathway.
The different anti-inflammatory mechanisms of the ApoA-I (显示 APOA1 抗体) cysteine mutants might be associated with the regulation of ATF3 level.
ATF3 is a new co-factor of c-Fos and NFATc1 (显示 NFATC1 抗体) to activate osteoclast differentiation and activity.
This study shows, for the first time, that alpha-lactalbumin (显示 LALBA 抗体) isolated in a rare 28kDa dimeric form induces cell death, while 14kDa (显示 SRP14 抗体) monomeric alpha-lactalbumin (显示 LALBA 抗体) is inactive.
Results show a pro-regenerative ATF3 function during PNS nerve regeneration involving transcriptional activation of a neuropeptide-encoding regeneration-associated gene cluster.
ATF3 appears to affect gonadotropin-stimulated progesterone secretion at a step or steps downstream of PKA signaling and before cholesterol conversion to progesterone.
ATF3 induction by acute hypoxia is mediated by nitric oxide and the JNK (显示 MAPK8 抗体) pathway in endothelial cells
Data indicate increasing expression for CREB (显示 CREB1 抗体), ATF1 (显示 AFT1 抗体), and ATF3 during gastrulation.
This gene encodes a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. This gene is induced by a variety of signals, including many of those encountered by cancer cells, and is involved in the complex process of cellular stress response. Multiple transcript variants encoding different isoforms have been found for this gene. It is possible that alternative splicing of this gene may be physiologically important in the regulation of target genes.
cyclic AMP-dependent transcription factor ATF-3
, activating transcription factor 3
, cAMP-dependent transcription factor ATF-3
, transcription factor LRG-21
, liver regeneration factor 1