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抗Human ATF3 抗体:
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抗Rat (Rattus) ATF3 抗体:
Human Polyclonal ATF3 Primary Antibody for IF (p), IHC (p) - ABIN669561
Hu, Li, Li: MARVELD1 Inhibits Nonsense-Mediated RNA Decay by Repressing Serine Phosphorylation of UPF1. in PLoS ONE 2013
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Human Polyclonal ATF3 Primary Antibody for ICC, IF - ABIN4282009
Wu, Nguyen, Dziunycz, Chang, Brooks, Lefort, Hofbauer, Dotto: Opposing roles for calcineurin and ATF3 in squamous skin cancer. in Nature 2010
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Human Monoclonal ATF3 Primary Antibody for RNAi, ELISA - ABIN559974
Chen, Huang, Chu, Chen, Chou, Wang, Kulp, Teng, Wang, Chen: Energy restriction-mimetic agents induce apoptosis in prostate cancer cells in part through epigenetic activation of KLF6 tumor suppressor gene expression. in The Journal of biological chemistry 2011
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Human Polyclonal ATF3 Primary Antibody for IHC (p), IHC - ABIN315461
Maciag, Nandurdikar, Hong, Chakrapani, Diwan, Morris, Shami, Shiao, Anderson, Keefer, Saavedra: Activation of the c-Jun N-terminal kinase/activating transcription factor 3 (ATF3) pathway characterizes effective arylated diazeniumdiolate-based nitric oxide-releasing anticancer prodrugs. in Journal of medicinal chemistry 2011
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Human Monoclonal ATF3 Primary Antibody for ELISA, WB - ABIN559976
Hsueh, Kuo, Chen: Transcriptional regulators of the ?Np63: their role in limbal epithelial cell proliferation. in Journal of cellular physiology 2012
Human Polyclonal ATF3 Primary Antibody for FACS, WB - ABIN1536715
Mo, Dai, Kang, Cui, He et al.: Ectopic expression of human MutS homologue 2 on renal carcinoma cells is induced by oxidative stress with interleukin-18 promotion via p38 mitogen-activated protein kinase (MAPK) and c-Jun N-terminal ... in The Journal of biological chemistry 2012
Data show that Atf3 was detected in retinal ganglion cell axons in both the nerve fiber layer and the optic nerve on the injured side.
Data show that ATF3 may be an important mediator of optic nerve regeneration-promoting gene expression in fish, a role which merits further investigation.
Altering TR4 (显示 NR2C2 抗体)-ATF3 signaling increases the efficacy of cisplatin to suppress hepatocellular carcinoma growth/progression.
ATF3 may be a potential early diagnostic biomarker for silicosis and ATF3 acts as a repressor in inflammatory responses induced by silica
The analysis showed higher urinary NGAL (显示 LCN2 抗体) and urinary ATF3 in patients with sepsis-AKI in comparison with patients with sepsis-non-AKI and healthy volunteers.
ATF3 mRNA and protein expression was significantly reduced in preterm Preeclamptic placentas. Therefore, reduced ATF3 may be centrally involved in the pathology of Preeclampsia.
Data suggest that suppression of nonsense-mediated RNA decay due to persistent DNA damage (from exposure to either mutagens, gamma rays, or oxidative stress) requires the activity of p38alpha (显示 MAPK14 抗体) MAPK (显示 MAPK1 抗体) (MAPK14 (显示 MAPK14 抗体), mitogen-activated protein kinase 14 (显示 MAPK14 抗体), MAP kinase p38 alpha (显示 MAPK14 抗体)); mRNA of ATF3 (activating transcription factor 3) is stabilized by persistent DNA damage in a p38alpha (显示 MAPK14 抗体) MAPK (显示 MAPK1 抗体)-dependent manner.
The microvascular injury phenotypes observed in vitro and in vivo were similar. ATF3 plays an important role in mediating brain microvascular responses to acute and chronic lipotoxic injury and may be an important preventative and therapeutic target for endothelial dysfunction in vascular cognitive impairment .
we have identified ATF3 as an important regulator of cisplatin cytotoxicity and that ATF3 inducers in combination with platins are a potential novel therapeutic approach for NSCLC.
reactivation of ATF3 is an important factor in determining sensitivity to pracinostat treatment, both in vitro and in vivo, and could serve as a potential biomarker of response and provide a rationale for therapeutic utility in HDACi-mediated treatments for bladder cancer.
these findings support roles for both cFOS (indirect) and ATF3 (direct) in effecting MMP13 (显示 MMP13 抗体) transcription in human chondrocytes.
We functionally validated several elements for metformin-induced promoter and enhancer activity. These include an enhancer in an ataxia telangiectasia mutated (ATM (显示 ATM 抗体)) intron that has SNPs in linkage disequilibrium .Using ChIP-seq and siRNA knockdown, we further show that activating transcription factor 3 (ATF3), our top metformin upregulated AMPK (显示 PRKAA1 抗体)-dependent gene, could have an important role in gluconeogenesis repression.
The different anti-inflammatory mechanisms of the ApoA-I (显示 APOA1 抗体) cysteine mutants might be associated with the regulation of ATF3 level.
ATF3 is a new co-factor of c-Fos and NFATc1 (显示 NFATC1 抗体) to activate osteoclast differentiation and activity.
This study shows, for the first time, that alpha-lactalbumin (显示 LALBA 抗体) isolated in a rare 28kDa dimeric form induces cell death, while 14kDa (显示 SRP14 抗体) monomeric alpha-lactalbumin (显示 LALBA 抗体) is inactive.
Results show a pro-regenerative ATF3 function during PNS nerve regeneration involving transcriptional activation of a neuropeptide-encoding regeneration-associated gene cluster.
Results reveal a critical role for ATF3 as a key regulator of the acinar cell transcriptional response during injury and may provide a link between chronic pancreatitis and PDAC.
The lung injury score and mortality were higher in ATF3 knock-out mice treated with Pseudomonas aeruginosa. Moreover, ATF3 was demonstrated to bind to lipopolysaccharide binding protein (显示 LBP 抗体). These findings suggest ATF3 protects mice against acute lung injury induced by Pseudomonas aeruginosa partly due to the binding to lipopolysaccharide binding protein (显示 LBP 抗体).
ATF3-KO mice escape from PE-dependent maladaptive cardiac remodeling by suppressing the IFNgamma-CXCL10 (显示 CXCL10 抗体)-CXCR3 (显示 CXCR3 抗体) axis at multiple levels.
ATF3 has a protective role in dampening the high fat-induced cardiac remodeling processes.
ATF3 protects against LPS (显示 TLR4 抗体)-induced acute lung injury by inhibiting TL1A (显示 TNFSF15 抗体) expression.
Myotube contraction increased ATF3 level, which modified chemokine (显示 CCL1 抗体) expression. In skeletal muscle after downhill running, ATF3 also modified chemokine (显示 CCL1 抗体) expression.
ATF3 appears to affect gonadotropin-stimulated progesterone secretion at a step or steps downstream of PKA signaling and before cholesterol conversion to progesterone.
ATF3 induction by acute hypoxia is mediated by nitric oxide and the JNK (显示 MAPK8 抗体) pathway in endothelial cells
Data indicate increasing expression for CREB (显示 CREB1 抗体), ATF1 (显示 AFT1 抗体), and ATF3 during gastrulation.
This gene encodes a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. This gene is induced by a variety of signals, including many of those encountered by cancer cells, and is involved in the complex process of cellular stress response. Multiple transcript variants encoding different isoforms have been found for this gene. It is possible that alternative splicing of this gene may be physiologically important in the regulation of target genes.
cyclic AMP-dependent transcription factor ATF-3
, activating transcription factor 3
, cAMP-dependent transcription factor ATF-3
, transcription factor LRG-21
, liver regeneration factor 1