ATF3 抗体 (Middle Region)
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- 抗原 See all ATF3 抗体
- ATF3 (Activating Transcription Factor 3 (ATF3))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼, Saccharomyces cerevisiae
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ATF3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- PLGVSITKAE VAPEEDERKK RRRERNKIAA AKCRNKKKEK TECLQKESEK
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%, Yeast: 75%, Zebrafish: 80%
- 产品特性
- This is a rabbit polyclonal antibody against ATF3. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human ATF3
- Top Product
- Discover our top product ATF3 Primary Antibody
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anti-Activating Transcription Factor 3 (ATF3) (AA 51-150) antibody
ATF3 适用: 人, 小鼠, 大鼠 WB, FACS, IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 3 (ATF3) (AA 1-181) antibodyATF3 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 6B8 unconjugated
anti-Activating Transcription Factor 3 (ATF3) (AA 1-181) antibodyATF3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 3 (ATF3) (AA 1-181) antibodyATF3 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 5A9B9 unconjugated
anti-Activating Transcription Factor 3 (ATF3) (AA 140-168) antibodyATF3 适用: 人 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 3 (ATF3) (AA 1-181) antibodyATF3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 3 (ATF3) (AA 113-130) antibodyATF3 适用: 人 WB, ELISA, IHC, FM 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 3 (ATF3) (C-Term) antibodyATF3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 3 (ATF3) (AA 140-168), (C-Term) antibodyATF3 适用: 人 WB, FACS 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 3 (ATF3) (C-Term) antibodyATF3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 181 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- ATF3 (Activating Transcription Factor 3 (ATF3))
- 别名
- ATF3 (ATF3 产品)
- 别名
- zgc:55526 antibody, ATF3 antibody, LRG-21 antibody, LRF-1 antibody, LRFI antibody, atf-3 antibody, activating transcription factor 3 antibody, activating transcription factor 3 L homeolog antibody, atf3 antibody, ATF3 antibody, Atf3 antibody, atf3.L antibody
- 背景
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This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. ATF3 represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter. Isoform 2 activates transcription presumably by sequestering inhibitory cofactors away from the promoters.Activating transcription factor 3 is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. Multiple transcript variants encoding two different isoforms have been found for this gene. The longer isoform represses rather than activates transcription from promoters with ATF binding elements. The shorter isoform (deltaZip2) lacks the leucine zipper protein-dimerization motif and does not bind to DNA, and it stimulates transcription presumably by sequestering inhibitory co-factors away from the promoter. It is possible that alternative splicing of the ATF3 gene may be physiologically important in the regulation of target genes.
Alias Symbols: -
Protein Interaction Partner: SUV39H1, BATF3, MAFF, CREB3, FOSL1, MAFG, JUNB, JUN, FOS, DDIT3, DBP, ATF2, CEBPG, CEBPE, CEBPA, ATF4, ATF3, BATF, HSP90AA1, SRA1, ZNF212, ID3, FHL2, SUMO1, SUMO3, HDAC10, HDAC5, HDAC6, HDAC4, HDAC3, HDAC1, SMARCA4, PDX1, ACTB, UBC, SUMO2, STAT1, MDM2, SM
Protein Size: 181 - 分子量
- 20 kDa
- 基因ID
- 467
- NCBI登录号
- NM_001674, NP_001665
- UniProt
- P18847
- 途径
- Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Unfolded Protein Response
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