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SIRT1 抗体

(Sirtuin 1 (SIRT1))

SIRT1 (Sirtuin 1) is a protein that plays a role in regulating metabolism and has been implicated in the development and progression of obesity. Several studies have investigated the potential of targeting SIRT1 as a therapeutic strategy for obesity.

Research has shown that SIRT1 is involved in the regulation of nutrient sensing and can modulate lipid and glucose metabolism. It has been found to protect against high-fat diet-induced metabolic damage and hepatic lipid accumulation. SIRT1 has also been shown to promote lipid metabolism and mitochondrial function, which are important processes in adipogenesis and obesity.

In addition, SIRT1 has been found to counteract aging- and obesity-related diseases by deacetylating many proteins. It has been suggested that targeting SIRT1 activity in the brain may show promise for the treatment of obesity and associated metabolic disorders.

SIRT1 antibodies are essential research tools for better understanding the role of SIRT1 in in regulating metabolism, lipid metabolism, and mitochondrial function.

SIRT1 抗体  (AA 101-200) SIRT1 抗体  (AA 101-200) SIRT1 抗体 (AA 101-200) (ABIN729853)

SIRT1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

SIRT1 抗体  (AA 456-555) SIRT1 抗体  (AA 456-555) SIRT1 抗体 (AA 456-555) (ABIN565071)

SIRT1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 7B7 unconjugated

SIRT1 抗体  (AA 448-747) SIRT1 抗体  (AA 448-747) SIRT1 抗体 (AA 448-747) (ABIN6147784)

SIRT1 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated

SIRT1 抗体 by Grade

Find SIRT1 抗体 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

SIRT1 抗体 by 适用

Find SIRT1 抗体 for a variety of species such as anti-Human SIRT1, anti-Mouse SIRT1, anti-Rat SIRT1. The species listed below are among those available. Click on a link to go to the corresponding products.

SIRT1 抗体 by 应用范围

Find SIRT1 抗体 validated for a specific application such as WB, ELISA, FACS, IF (cc). Some of the available applications are listed below. Click on a link to go to the corresponding products.

SIRT1 抗体 by 抗体来源

Find SIRT1 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

SIRT1 抗体 by 抗原表位

Find SIRT1 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

SIRT1 抗体 by 克隆形成能力

Find available monoclonal or polyclonal SIRT1 抗体. Click on a link to go to the corresponding products.

SIRT1 抗体 by 克隆

Find SIRT1 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

SIRT1 抗体 by 标记

Find SIRT1 抗体 with a specific conjugate such as Biotin, FITC, Alexa Fluor 488. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular SIRT1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (5)
  • (7)
Cat. No. ABIN729853
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC (p)
Validations
  • (3)
  • (5)
Cat. No. ABIN565071
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, IF
Validations
  • (9)
Cat. No. ABIN6147784
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IF, IHC (p)
Validations
  • (1)
  • (4)
Cat. No. ABIN6242824
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, FACS, ICC
Validations
  • (2)
  • (4)
Cat. No. ABIN969396
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, IF, ChIP
Validations
  • (4)
Cat. No. ABIN7270322
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application WB
Validations
  • (5)
  • (4)
Cat. No. ABIN2779607
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC (p), EIA
Validations
  • (5)
Cat. No. ABIN614713
Quantity 50 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC, IF
Validations
  • (5)
Cat. No. ABIN3032583
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Dog, Human, Mouse, Rat
Application WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (4)
  • (2)
Cat. No. ABIN745658
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (3)
Cat. No. ABIN7435913
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF, IHC (p)
Validations
  • (3)
Cat. No. ABIN7251247
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application IF (cc), IHC (p)
Validations
  • (2)
Cat. No. ABIN5557342
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (2)
Cat. No. ABIN7160851
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (2)
Cat. No. ABIN7435916
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our SIRT1 抗体

Zbroch, Bazyluk, Malyszko, Koc-Zorawska, Rydzewska-Rosolowska, Kakareko, Hryszko: "The Serum Concentration of Anti-Aging Proteins, Sirtuin1 and αKlotho in Patients with End-Stage Kidney Disease on Maintenance Hemodialysis." in: Clinical interventions in aging, Vol. 15, pp. 387-393, (2020) (PubMed).

Yang, Wang, He, Liu, Chen, Wang, Wang, Wang: "Trimetazidine Inhibits Renal Tubular Epithelial Cells to Mesenchymal Transition in Diabetic Rats via Upregulation of Sirt1." in: Frontiers in pharmacology, Vol. 11, pp. 1136, (2020) (PubMed).

Ascenzi, Barberi, Dobrowolny, Villa Nova Bacurau, Nicoletti, Rizzuto, Rosenthal, Scicchitano, Musarò: "Effects of IGF-1 isoforms on muscle growth and sarcopenia." in: Aging cell, Vol. 18, Issue 3, pp. e12954, (2019) (PubMed).

Takata, Sakasai-Sakai, Takino, Takeuchi: "Evidence for Toxic Advanced Glycation End-Products Generated in the Normal Rat Liver." in: Nutrients, Vol. 11, Issue 7, (2019) (PubMed).

Yanes, Zhang, Shen, Weyand, Goronzy: "Metabolic reprogramming in memory CD4 T cell responses of old adults." in: Clinical immunology (Orlando, Fla.), Vol. 207, pp. 58-67, (2019) (PubMed).

Zhang, Abdukerim, Abilailieti, Tang, Ling, Pan: "The protective effects of orexin a against high glucose-induced activation of NLRP3 inflammasome in human vascular endothelial cells." in: Archives of biochemistry and biophysics, Vol. 672, pp. 108052, (2019) (PubMed).

Piao, Zhao, Zhu, Inoue, Shibata, Lei, Hu, Yu, Yang, Wu, Xu, Okumura, Ouchi, Murohara, Kuzuya, Cheng: "Chronic Psychological Stress Accelerates Vascular Senescence and Impairs Ischemia-Induced Neovascularization: The Role of Dipeptidyl Peptidase-4/Glucagon-Like Peptide-1-Adiponectin Axis." in: Journal of the American Heart Association, Vol. 6, Issue 10, (2018) (PubMed).

Zang, Fan, Chen, Huang, Qin: "Improvement of Lipid and Glucose Metabolism by Capsiate in Palmitic Acid-Treated HepG2 Cells via Activation of the AMPK/SIRT1 Signaling Pathway." in: Journal of agricultural and food chemistry, Vol. 66, Issue 26, pp. 6772-6781, (2018) (PubMed).

Zeng, Hu, He, Wang, Li, Xiong, Ye: "Hypothermic machine perfusion ameliorates inflammation during ischemia‑reperfusion injury via sirtuin‑1‑mediated deacetylation of nuclear factor‑κB p65 in rat livers donated after circulatory death." in: Molecular medicine reports, Vol. 16, Issue 6, pp. 8649-8656, (2018) (PubMed).

Zhang, Zhang, Guo, Zeng, Wu, Liu, He, Wang, Huang, Chen: "Sirt1 Protects Endothelial Cells against LPS-Induced Barrier Dysfunction." in: Oxidative medicine and cellular longevity, Vol. 2017, pp. 4082102, (2018) (PubMed).

Aliases for SIRT1 抗体

sirtuin 1 (SIRT1) 抗体
sirtuin 1 (SRT1) 抗体
sirtuin 1 (Sirt1) 抗体
sirtuin 1 L homeolog (sirt1.L) 抗体
AA673258 抗体
Sir2 抗体
SIR2 抗体
Sir2a 抗体
Sir2alpha 抗体
SIR2L1 抗体
sir2l1 抗体
sirtuin 抗体
sirtuin 1 抗体
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