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KPNA2 抗体

(Karyopherin alpha 2 (RAG Cohort 1, Importin alpha 1) (KPNA2))
The import of proteins into the nucleus is a process that involves at least 2 steps. The first is an energy-independent docking of the protein to the nuclear envelope and the second is an energy-dependent translocation through the nuclear pore complex. Imported proteins require a nuclear localization sequence (NLS) which generally consists of a short region of basic amino acids or 2 such regions spaced about 10 amino acids apart. Proteins involved in the first step of nuclear import have been identified in different systems. These include the Xenopus protein importin and its yeast homolog, SRP1 (a suppressor of certain temperature-sensitive mutations of RNA polymerase I in Saccharomyces cerevisiae), which bind to the NLS. KPNA2 protein interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in the nuclear transport of proteins. KPNA2 also may play a role in V(D)J recombination [provided by RefSeq, Jul 2008].

70 results :

KPNA2 适用: 人, 小鼠 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 1E8B7 unconjugated
产品编号 ABIN5542626
 
KPNA2 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7156118
 
Verified KPNA2 适用: 人, 大鼠 WB, IHC, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN185157
 
KPNA2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
Pubmed 1 reference
产品编号 ABIN3022267
 
KPNA2 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
Pubmed 1 reference
产品编号 ABIN2856324
 
KPNA2 适用: 人 WB, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7435853
 
KPNA2 适用: 人 WB, IF, ICC, FACS 宿主: 小鼠 Monoclonal C10 unconjugated
产品编号 ABIN7427135
 
KPNA2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7307970
 
KPNA2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
产品编号 ABIN561615
 
KPNA2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
产品编号 ABIN517371
 
KPNA2 适用: 人, 小鼠, 大鼠, 犬, 马, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6741264
 
KPNA2 适用: 人 WB 宿主: 大鼠 Monoclonal 2G7 unconjugated
产品编号 ABIN341119
 
KPNA2 适用: 人, 小鼠 WB, IF, ICC 宿主: 大鼠 Monoclonal 2G7 unconjugated
产品编号 ABIN108571
 
Verified KPNA2 适用: 人 WB, ELISA, IF 宿主: 山羊 Polyclonal Biotin
产品编号 ABIN5539841
 
KPNA2 适用: 人 宿主: 兔 Polyclonal FITC
产品编号 ABIN7156120
 
KPNA2 适用: 人 ELISA 宿主: 兔 Polyclonal Biotin
产品编号 ABIN7156119
 
KPNA2 适用: 人 ELISA 宿主: 兔 Polyclonal HRP
产品编号 ABIN7156121
 
KPNA2 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C19 unconjugated
产品编号 ABIN7641672
 
KPNA2 适用: 人 WB, IHC, ICC, IP 宿主: 小鼠 Monoclonal C18 unconjugated
产品编号 ABIN7641671
 
KPNA2 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C8 unconjugated
产品编号 ABIN7641670
 
  • 类型 Primary
    • Primary
  • 应用范围
    • Western Blotting (WB)
    • Immunohistochemistry (IHC)
    • Immunocytochemistry (ICC)
    • Flow Cytometry (FACS)
    • Immunofluorescence (IF)
    • ELISA
    • Immunoprecipitation (IP)
    • Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    • Immunochromatography (IC)
    • Enzyme Immunoassay (EIA)
    • Immunofluorescence (fixed cells) (IF/ICC)
  • 适用
    • Human
    • Mouse
    • Rat
    • Dog
    • Horse
    • Rabbit
    • Cow
    • Guinea Pig
    • Monkey
    • Pig
  • 论文引用
  • 图像
  • Carrier free only
  • 抗体来源
    • Rabbit
    • Mouse
    • Goat
    • Rat
    • Sheep
  • 克隆形成能力
    • Polyclonal
    • Monoclonal
  • 克隆
    • C8
    • 12K121
    • 2G7
    • C10
    • C11
    • C18
    • C19
    • C4
    • C6
    • C7
    • C9
    • 11n120
    • 1E8B7
    • AEAF-11
  • 抗原表位
    • AA 157-412
    • AA 2-285
    • AA 2-132
    • C-Term
    • AA 1-132
    • AA 1-529
    • AA 468-529
    • N-Term
    • AA 1-290
    • AA 1-50
    • AA 1-530
    • AA 116-515
    • AA 2-46
    • AA 323-372
    • AA 40-90
    • AA 420-528
    • AA 51-529
    • Middle Region
  • 标记
    • 非结合性
    • Biotin
    • Alexa Fluor 488
    • Alexa Fluor 555
    • Alexa Fluor 594
    • Alexa Fluor 647
    • Alexa Fluor 680
    • Alexa Fluor 750
    • FITC
    • HRP
  • 抗体亚型
    • IgG
    • IgG1
    • IgG2a
    • IgG2b kappa
    • IgG1 kappa
    • IgG2a kappa
  • 蛋白类型
    • Recombinant Antibody
  • Format
    • Liquid
    • Lyophilized
  • Grade
    • Verified
  • Supplier
    • antibodies-online
    • Signalway
    • Biomatik
    • Abbexa
    • Boster Bio
    • USBio
    • Acris
    • Aviva Systems Biology
    • Cohesion Biosciences
    • NSJ Bioreagents

Latest Publications for our KPNA2 抗体

Ye, Chen, Li, Zhao, He, Zohaib, Song, Deng, Zhang, Chen, Cao: "Japanese Encephalitis Virus NS5 Inhibits Type I Interferon (IFN) Production by Blocking the Nuclear Translocation of IFN Regulatory Factor 3 and NF-κB." in: Journal of virology, Vol. 91, Issue 8, (2017) (PubMed).

Yajima, Wessel: "Essential elements for translation: the germline factor Vasa functions broadly in somatic cells." in: Development (Cambridge, England), Vol. 142, Issue 11, pp. 1960-70, (2015) (PubMed).

Jeong, Kim, Lee, Cha, Khadka, Cho, Chung: "Akt-mediated phosphorylation increases the binding affinity of hTERT for importin α to promote nuclear translocation." in: Journal of cell science, Vol. 128, Issue 12, pp. 2287-301, (2015) (PubMed).

Sun, van Koningsbruggen, Long, Straasheijm, Klooster, Jones, Bellini, Levesque, Brieher, van der Maarel, Jones: "Facioscapulohumeral muscular dystrophy region gene 1 is a dynamic RNA-associated and actin-bundling protein." in: Journal of molecular biology, Vol. 411, Issue 2, pp. 397-416, (2011) (PubMed).

Ishiguro, Ando, Maeda, Watanabe, Goto: "Cutting edge: tubulin ? functions as an adaptor in NFAT-importin ? interaction." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 186, Issue 5, pp. 2710-3, (2011) (PubMed).

Sato, Maquat: "Remodeling of the pioneer translation initiation complex involves translation and the karyopherin importin beta." in: Genes & development, Vol. 23, Issue 21, pp. 2537-50, (2009) (PubMed).

Jeffrey, Chng, ODell, Martin: "Activity-dependent anchoring of importin alpha at the synapse involves regulated binding to the cytoplasmic tail of the NR1-1a subunit of the NMDA receptor." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 29, Issue 50, pp. 15613-20, (2009) (PubMed).

Grozinger, Schreiber: "Regulation of histone deacetylase 4 and 5 and transcriptional activity by 14-3-3-dependent cellular localization." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, Issue 14, pp. 7835-40, (2000) (PubMed).

Moroianu, Blobel, Radu: "Previously identified protein of uncertain function is karyopherin alpha and together with karyopherin beta docks import substrate at nuclear pore complexes." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, Issue 6, pp. 2008-11, (1995) (PubMed).

Moroianu, Hijikata, Blobel, Radu: "Mammalian karyopherin alpha 1 beta and alpha 2 beta heterodimers: alpha 1 or alpha 2 subunit binds nuclear localization signal and beta subunit interacts with peptide repeat-containing nucleoporins." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, Issue 14, pp. 6532-6, (1995) (PubMed).

Aliases for KPNA2 抗体

karyopherin subunit alpha 2 (KPNA2) 抗体
importin subunit alpha-2 (EDI_246290) 抗体
importin subunit alpha-2 (EDI_335040) 抗体
Importin subunit alpha-2 (ima2) 抗体
karyopherin subunit alpha 2 (Kpna2) 抗体
karyopherin (importin) alpha 2 (Kpna2) 抗体
karyopherin alpha-2 subunit like L homeolog (kpna2.L) 抗体
karyopherin alpha 2 (RAG cohort 1, importin alpha 1) (kpna2) 抗体
2410044B12Rik 抗体
hm:zeh0389 抗体
hm:zeh0389r 抗体
ima2 抗体
importin 抗体
IPOA1 抗体
ipoa1 抗体
kpna2 抗体
PTAC58 抗体
QIP2 抗体
qip2 抗体
RCH1 抗体
Rch1 抗体
rch1 抗体
SRP1alpha 抗体
srp1alpha 抗体
zgc:86945 抗体
zgc:113902 抗体
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