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TNFSF4 ELISA 试剂盒

TNFSF4 适用: 人 Colorimetric Sandwich ELISA 156 pg/mL - 10000 pg/mL Cell Culture Supernatant, Plasma (EDTA - heparin), Serum
产品编号 ABIN6720118
发货至: 中国
  • 抗原 See all TNFSF4 ELISA试剂盒
    TNFSF4 (Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4))
    适用
    • 4
    • 3
    • 1
    检测方法
    Colorimetric
    实验类型
    Sandwich ELISA
    检测范围
    156 pg/mL - 10000 pg/mL
    最低检测浓度
    156 pg/mL
    应用范围
    ELISA
    原理
    Sandwich ELISA for Quantitative Detection of Antigen
    样品类型
    Cell Culture Supernatant, Plasma (EDTA - heparin), Serum
    Analytical Method
    Quantitative
    产品特性

    Synonyms: CD 134L, CD 252, CD134, CD134 ligand, CD134L, CD252, CD252 antigen, glycoprotein 34 kd, Glycoprotein Gp34, GP34, OX-40L, OX40 antigen ligand, OX40 ligand, OX40L, TAX transcriptionally-activated glycoprotein 1, TNFL4_HUMAN, Tnfsf4, Tumor necrosis factor (ligand) superfamily member 4, Tumor necrosis factor ligand superfamily member 4, TXGP1

    Background: OX40L is the ligand for CD134 and is expressed on such cells as DC2s enabling amplification of Th2 cell differentiation. OX40L has also been designated CD252. By analysis of an interspecific backcross, the mouse Tnfsf4 gene is mapped to chromosome 1. Using fluorescence in situ hybridization, they localized the human TNFSF4 gene to 1q25, a region sharing homology of synteny with the portion of mouse chromosome 1 containing the Tnfsf4 gene. OX40L strongly inhibited the generation of IL-10-producing Tr1 cells induced by two physiologic stimuli, the inducible costimulatory ligand and immature dendritic cells. In addition, OX40L strongly inhibited IL-10 production and suppressive function of differentiated IL-10-producing Tr1 cells. Tnfsf4 underlies Ath1 in mice and that polymorphisms in its human homolog TNFSF4 increase the risk of myocardial infarction in humans.

    Gene Name: TNFSF4

    Production: Natural and recombinant human TNFSF4. There is no detectable cross-reactivity with other relevant proteins.

    Standard: Expression system for standard: NSO, Immunogen sequence: Q51-L183

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    Discover our top product TNFSF4 ELISA Kit
  • 应用备注

    Application Note: Useful in Sandwich ELISA for Quantitative Detection of Antigen. Aliquot 0.1 mL per well of the 10000pg/mL, 5000pg/mL, 2500pg/mL, 1250pg/mL, 625pg/mL, 313pg/mL, 156pg/mL human TNFSF4 standard solutions into the precoated 96-well plate. Add 0.1 mL of the sample diluent buffer into the control well (Zero well). Add 0.1 mL of each properly diluted sample of human cell culture supernates, serum or plasma (heparin, EDTA) to each empty well. It is recommended that each human TNFSF4 standard solution and each sample be measured in duplicate.

    Blood Product Anticoagulant: Heparin Sodium

    ELISA Dilution: 156pg/mL-10000pg/mL

    Other Performance Data: DOE: 2-8° C - 03/18/19 -20° C - 09/18/19

    样本量
    100 μL
    板类型
    Pre-coated
    限制
    仅限研究用
  • 储存条件
    RT,4 °C,-20 °C
    储存方法
    Store vials at 4°C prior to opening. Centrifuge product if not completely clear after standing at room temperature. This product is stable for 6 months at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage freeze at -20°C or below for 12 months. Avoid cycles of freezing and thawing.
  • 抗原 See all TNFSF4 ELISA试剂盒
    TNFSF4 (Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4))
    别名
    TNFSF4 - OX40L (TNFSF4 产品)
    别名
    TNFSF4 ELISA Kit, OX40L ELISA Kit, TNFRSF4 ELISA Kit, CD134L ELISA Kit, CD252 ELISA Kit, GP34 ELISA Kit, OX-40L ELISA Kit, OX4OL ELISA Kit, TXGP1 ELISA Kit, Ath-1 ELISA Kit, Ath1 ELISA Kit, Ox40l ELISA Kit, Txgp1l ELISA Kit, gp34 ELISA Kit, TNF superfamily member 4 ELISA Kit, tumor necrosis factor (ligand) superfamily, member 4 ELISA Kit, TNFSF4 ELISA Kit, Tnfsf4 ELISA Kit
    基因ID
    7292
    NCBI登录号
    NP_001284491
    UniProt
    P23510
    途径
    Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation, Cancer Immune Checkpoints
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