KDM5A 产品
(Lysine (K)-Specific Demethylase 5A (KDM5A))
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The protein encoded by this gene is a ubiquitously expressed nuclear protein. It binds directly, with several other proteins, to retinoblastoma protein which regulates cell proliferation. This protein also interacts with rhombotin-2 which functions distinctly in erythropoiesis and in T-cell leukemogenesis. Rhombotin-2 is thought to either directly affect the activity of the encoded protein or may indirectly modulate the functions of the retinoblastoma protein by binding to this protein. [provided by RefSeq, Mar 2010].
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Featured KDM5A Categories
Recommended KDM5A 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF, FACS
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- (3)
- (6)
Cat. No.
ABIN3201015
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP, ChIP
Validations
- (4)
Cat. No.
ABIN7268330
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
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Validations
- (3)
Cat. No.
ABIN562597
Quantity
100 μg
Datasheet
Datasheet
Recommended KDM5A ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6975003
Quantity
96 tests
Datasheet
Datasheet
Recommended KDM5A 蛋白
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Reactivity
Source
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Datasheet
Reactivity
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Source
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- (3)
Cat. No.
ABIN2669680
Quantity
20 μg
Datasheet
Datasheet
Reactivity
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Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1308284
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN5709797
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our KDM5A Products
: "Identification of ryuvidine as a KDM5A inhibitor." in: Scientific reports, Vol. 9, Issue 1, pp. 9952, (2019) (PubMed).: "Vitamin C promotes pluripotency of human induced pluripotent stem cells via the histone demethylase JARID1A." in: Biological chemistry, Vol. 397, Issue 11, pp. 1205-1213, (2016) (PubMed).
: "Increased progesterone receptor A expression in labouring human myometrium is associated with decreased promoter occupancy by the histone demethylase JARID1A." in: Molecular human reproduction, Vol. 20, Issue 5, pp. 442-53, (2014) (PubMed).
: "Chromatin remodeling: recruitment of histone demethylase RBP2 by Mad1 for transcriptional repression of a Myc target gene, telomerase reverse transcriptase." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 24, Issue 2, pp. 579-86, (2010) (PubMed).
: "Histone demethylase KDM5A is an integral part of the core Notch-RBP-J repressor complex." in: Genes & development, Vol. 24, Issue 6, pp. 590-601, (2010) (PubMed).
: "Genome-wide analysis of the H3K4 histone demethylase RBP2 reveals a transcriptional program controlling differentiation." in: Molecular cell, Vol. 31, Issue 4, pp. 520-30, (2008) (PubMed).
: "p53-targeted LSD1 functions in repression of chromatin structure and transcription in vivo." in: Molecular and cellular biology, Vol. 28, Issue 17, pp. 5139-46, (2008) (PubMed).
: "RBP2 belongs to a family of demethylases, specific for tri-and dimethylated lysine 4 on histone 3." in: Cell, Vol. 128, Issue 6, pp. 1063-76, (2007) (PubMed).
: "The retinoblastoma binding protein RBP2 is an H3K4 demethylase." in: Cell, Vol. 128, Issue 5, pp. 889-900, (2007) (PubMed).
Synonyms and alternative names related to KDM5A
lysine demethylase 5A (Kdm5a), lysine demethylase 5A (KDM5A), lysine (K)-specific demethylase 5A (Kdm5a), AA409370, C76986, Jarid1a, JARID1A, RBBP-2, RBBP2, Rbbp2, RBP2Protein level used designations for KDM5A
- jumonji, AT rich interactive domain 1A (Rbp2 like)
- lysine-specific demethylase 5A
- jumonji, AT rich interactive domain 1A
- lysine (K)-specific demethylase 5A
- JARID1A variant protein-like
- jumonji AT-rich interactive domain 1A
- retinoblastoma binding protein 2
- Jumonji, AT rich interactive domain 1A (RBP2-like)
- histone demethylase JARID1A
- jumonji/ARID domain-containing protein 1A
- RBBP-2
- retinoblastoma-binding protein 2
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