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KDELR1 产品

(KDEL (Lys-Asp-Glu-Leu) Endoplasmic Reticulum Protein Retention Receptor 1 (KDELR1))

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Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, which is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. The protein encoded by this gene was the first member of the family to be identified, and it encodes a protein structurally and functionally similar to the yeast ERD2 gene product. [provided by RefSeq, Jul 2008].

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Featured KDELR1 Categories

KDELR1 抗体

High quality antibodies with extensive validation data.

KDELR1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended KDELR1 抗体

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Reactivity
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Validations
Cat. No.
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Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF, ICC, ELISA, IHC
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Cat. No. ABIN6262763
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Human, Monkey, Mouse, Rat
Application WB, IP, ICC, IHC
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Cat. No. ABIN1742422
Quantity 50 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p), FACS, IF (cc), IF (p)
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Cat. No. ABIN6943880
Quantity 100 μL
Datasheet Datasheet

Recommended KDELR1 蛋白

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Reactivity
Source
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Source Wheat germ
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Quantity 10 μg
Datasheet Datasheet
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Source Insect Cells
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Cat. No. ABIN3097037
Quantity 1 mg
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Cat. No. ABIN3127873
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Latest Publications for our KDELR1 Products

Henderson, Richie, Airavaara, Wang, Harvey: "Mesencephalic astrocyte-derived neurotrophic factor (MANF) secretion and cell surface binding are modulated by KDEL receptors." in: The Journal of biological chemistry, Vol. 288, Issue 6, pp. 4209-25, (2013) (PubMed).

Synonyms and alternative names related to KDELR1

KDEL endoplasmic reticulum protein retention receptor 1 (KDELR1), KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 (Kdelr1), KDEL endoplasmic reticulum protein retention receptor 1 (Kdelr1), 8030486F04Rik, AW215843, ERD2, ERD2.1, Erd2.1, HDEL, PM23

Protein level used designations for KDELR1

  • ER lumen protein retaining receptor 1
  • KDEL endoplasmic reticulum protein retention receptor 1
  • KDEL receptor 1
  • putative MAPK-activating protein PM23
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