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KDM4B 产品

(Lysine (K)-Specific Demethylase 4B (KDM4B))

Categories

Histone demethylase that specifically demethylates 'Lys- 9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.

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Featured KDM4B Categories

KDM4B 抗体

High quality antibodies with extensive validation data.

KDM4B 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended KDM4B 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF, IP
Validations
  • (4)
Cat. No. ABIN7268329
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC, FACS, ICC, Neut
Validations
  • (4)
Cat. No. ABIN5611347
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB, IF, IP, ICC
Validations
  • (3)
Cat. No. ABIN6972226
Quantity 100 μL
Datasheet Datasheet

Recommended KDM4B 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3093321
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3136790
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Baculovirus infected Insect Cells, Insect cells (Sf9), Mouse
Validations
Cat. No. ABIN6700238
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our KDM4B Products

Xu, Moresco, Chang, Mukim, Smith, Diedrich, Yates, Jones: "SHMT2 and the BRCC36/BRISC deubiquitinase regulate HIV-1 Tat K63-ubiquitylation and destruction by autophagy." in: PLoS pathogens, Vol. 14, Issue 5, pp. e1007071, (2018) (PubMed).

Kim, Jung, Nagappan, Jung: "Histone H3K9 demethylase JMJD2B induces hepatic steatosis through upregulation of PPARγ2." in: Scientific reports, Vol. 8, Issue 1, pp. 13734, (2018) (PubMed).

Uribe, Buzzi, Bronner, Strobl-Mazzulla: "Histone demethylase KDM4B regulates otic vesicle invagination via epigenetic control of Dlx3 expression." in: The Journal of cell biology, Vol. 211, Issue 4, pp. 815-27, (2015) (PubMed).

Mallette, Mattiroli, Cui, Young, Hendzel, Mer, Sixma, Richard: "RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites." in: The EMBO journal, Vol. 31, Issue 8, pp. 1865-78, (2012) (PubMed).

Toyokawa, Cho, Iwai, Yoshimatsu, Takawa, Hayami, Maejima, Shimizu, Tanaka, Tsunoda, Field, Kelly, Neal, Ponder, Maehara, Nakamura, Hamamoto: "The histone demethylase JMJD2B plays an essential role in human carcinogenesis through positive regulation of cyclin-dependent kinase 6." in: Cancer prevention research (Philadelphia, Pa.), Vol. 4, Issue 12, pp. 2051-61, (2011) (PubMed).

Beyer, Kristensen, Jensen, Johansen, Staller: "The histone demethylases JMJD1A and JMJD2B are transcriptional targets of hypoxia-inducible factor HIF." in: The Journal of biological chemistry, Vol. 283, Issue 52, pp. 36542-52, (2008) (PubMed).

Synonyms and alternative names related to KDM4B

lysine demethylase 4B (KDM4B), lysine (K)-specific demethylase 4B (kdm4b), lysine (K)-specific demethylase 4B (KDM4B), lysine demethylase 4B (kdm4b), lysine (K)-specific demethylase 4B (Kdm4b), 4732474L06Rik, JMJD2B, jmjd2b, Jmjd2b, KDM4B, mKIAA0876, si:ch211-124a3.4, TDRD14B

Protein level used designations for KDM4B

  • lysine (K)-specific demethylase 4B
  • jumonji domain containing 2B
  • lysine-specific demethylase 4B
  • lysine-specific demethylase 4B-like
  • jmjC domain-containing histone demethylation protein 3B
  • jumonji domain-containing protein 2B
  • tudor domain containing 14B
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