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Insulin-Like Growth Factor 1 Receptor 产品

(Insulin-Like Growth Factor 1 Receptor (IGF1R))

Categories

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. [provided by RefSeq, Jul 2008].

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Featured Insulin-Like Growth Factor 1 Receptor Categories

Insulin-Like Growth Factor 1 Receptor 抗体

High quality antibodies with extensive validation data.

Insulin-Like Growth Factor 1 Receptor ELISA试剂盒

Reliable ELISA kits for a wide range of species.

Insulin-Like Growth Factor 1 Receptor 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Insulin-Like Growth Factor 1 Receptor 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Dog, Human, Mouse, Rat
Application FACS
Validations
  • (2)
  • (3)
  • (1)
Cat. No. ABIN726575
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (8)
Cat. No. ABIN6256637
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, IP, ICC
Validations
  • (5)
Cat. No. ABIN6256620
Quantity 100 μL
Datasheet Datasheet

Recommended Insulin-Like Growth Factor 1 Receptor ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6956791
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6967638
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6962020
Quantity 96 tests
Datasheet Datasheet

Recommended Insulin-Like Growth Factor 1 Receptor 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (5)
Cat. No. ABIN7274862
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7274863
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Insect cells (Sf21)
Validations
  • (2)
Cat. No. ABIN5570157
Quantity 5 μg
Datasheet Datasheet

Latest Publications for our Insulin-Like Growth Factor 1 Receptor Products

Mir, Albrecht, Ali, Hansson, Maak: "MicroRNA-100 Reduced Fetal Bovine Muscle Satellite Cell Myogenesis and Augmented Intramuscular Lipid Deposition by Modulating IGF1R." in: Cells, Vol. 11, Issue 3, (2022) (PubMed).

Yao, Zhu, Fang, Yang, Chen, Jin, Zhao, Zhao, Zhuang, Chen, Shen: "Insulin-Like Growth Factor-1 and Receptor Contribute Genetic Susceptibility to Hypertension in a Han Chinese Population." in: American journal of hypertension, Vol. 31, Issue 4, pp. 422-430, (2019) (PubMed).

De Martino, van Koetsveld, Feelders, de Herder, Dogan, Janssen, Hofste Op Bruinink, Pivonello, Waaijers, Colao, de Krijger, Pivonello, Hofland: "IGF and mTOR pathway expression and in vitro effects of linsitinib and mTOR inhibitors in adrenocortical cancer." in: Endocrine, Vol. 64, Issue 3, pp. 673-684, (2019) (PubMed).

Lai, Chen, Chen, Ruan, He, Chen, Tang, Wang: "Overexpression of decorin promoted angiogenesis in diabetic cardiomyopathy via IGF1R-AKT-VEGF signaling." in: Scientific reports, Vol. 7, pp. 44473, (2018) (PubMed).

Liu, Ma, Li, Yu, Zhou, Lu, Jin, Wang, Yu: "Hsa-let-7c controls the committed differentiation of IGF-1-treated mesenchymal stem cells derived from dental pulps by targeting IGF-1R via the MAPK pathways." in: Experimental & molecular medicine, Vol. 50, Issue 4, pp. 25, (2018) (PubMed).

Wang, Huang, Yu, Li, Huang, Mo, Gao, Zhou, Hu: "Two prostate cancer‑associated polymorphisms in the 3'UTR of IGF1R influences prostate cancer susceptibility by affecting miRNA binding." in: Oncology reports, Vol. 41, Issue 1, pp. 512-524, (2018) (PubMed).

Ye, Chan, Waters, Bess, Harned, Wei, Loncarek, Luke, Orsburn, Hollinger, Stephens, Bagni, Martinko, Wells, Nissley, McCormick, Whiteley, Blonder: "Comparative proteomics of a model MCF10A-KRasG12V cell line reveals a distinct molecular signature of the KRasG12V cell surface." in: Oncotarget, Vol. 7, Issue 52, pp. 86948-86971, (2018) (PubMed).

Zhao, Feng, Zhang, Kou, Li, Liu, Zhang, Cui, Chu, Shen, Min: "Inhibition of peripubertal sheep mammary gland development by cysteamine through reducing progesterone and growth factor production." in: Theriogenology, Vol. 89, pp. 280-288, (2017) (PubMed).

Chu, Zhao, Feng, Zhang, Liu, Cheng, Li, Shen, Cao, Li, Min: "MicroRNA-126 participates in lipid metabolism in mammary epithelial cells." in: Molecular and cellular endocrinology, Vol. 454, pp. 77-86, (2017) (PubMed).

Ramdhave, Ojha, Nandave: "Energy intake correlates with the levels of fatty acid synthase and insulin-like growth factor-1 in male and female C57BL/6 mice." in: American journal of translational research, Vol. 9, Issue 3, pp. 830-844, (2017) (PubMed).

Synonyms and alternative names related to Insulin-Like Growth Factor 1 Receptor

alanyl-tRNA synthetase (AARS), insulin like growth factor 1 receptor (IGF1R), insulin-like growth factor 1 receptor (Igf1r), insulin like growth factor 1 receptor (igf1r), insulin-like growth factor 1 (Igf1), insulin-like growth factor I receptor (Igf1r), insulin-like growth factor I receptor (LOC780503), insulin-like growth factor 1 receptor (LOC100136427), insulin like growth factor 1 receptor S homeolog (igf1r.S), insulin like growth factor 1 receptor (Igf1r), insulin-like growth factor 1b receptor (igf1rb), insulin-like growth factor 1a receptor (igf1ra), A330103N21Rik, CD221, CMT2N, D930020L01, DKFZp469I0618, hyft, IGF-1R, igf-1r, igf-ir, IGF-IR, IGF-IRa, IGF-IRb, IGF1R, IGFIR, IGFIRC, IGFR, IGFR1, JTK13, sb:eu1090, wu:fb03h06, wu:fi20b10, xIGF-1R, xigf1r, xIGFR

Protein level used designations for Insulin-Like Growth Factor 1 Receptor

  • alaRS
  • alanine tRNA ligase 1, cytoplasmic
  • alanine--tRNA ligase, cytoplasmic
  • alanyl-tRNA synthetase, cytoplasmic
  • renal carcinoma antigen NY-REN-42
  • IGF-I receptor
  • insulin-like growth factor I receptor
  • soluble IGF1R variant 1
  • soluble IGF1R variant 2
  • insulin-like growth factor receptor tyrosine kinase
  • insulin-like growth factor-I receptor
  • type 1 IGF receptor
  • tyrosine kinase
  • IGF-1 receptor
  • insulin-like growth factor 1 receptor beta subunit
  • insulin-like growth factor receptor 1
  • insulin-like growth factor-1 receptor
  • receptor tyrosine kinase
  • insulin-like growth factor 1 receptor
  • IGF-I
  • insulin-like growth factor I
  • somatomedin
  • line 186
  • insulin-like growth factor-1 receptor beta subunit
  • xIGF-1R
  • xIGFR
  • insulin-like growth factor 1b receptor
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