GRB2 抗体
(Growth Factor Receptor-Bound Protein 2 (GRB2))
The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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83 results
Independently Validated
GRB2
适用: 人, 小鼠, 大鼠, 犬, 小鸡, Cow, Pig, 猴, 斑马鱼, 豚鼠, 马, 兔, Hamster, Bat, 非洲爪蟾
WB
宿主: 兔
Polyclonal
unconjugated
1 image
Latest Publications for our GRB2 抗体
: "Targeting the C-terminal focal adhesion kinase scaffold in pancreatic cancer." in: Cancer letters, Vol. 353, Issue 2, pp. 281-9, (2014) (PubMed).: "An analysis of the phosphoproteome of immune cell lines exposed to the immunomodulatory mycotoxin deoxynivalenol." in: Biochimica et biophysica acta, Vol. 1814, Issue 7, pp. 850-7, (2011) (PubMed).
: "Coupling of Grb2 to Gab1 mediates hepatocyte growth factor-induced high intensity ERK signal required for inhibition of HepG2 hepatoma cell proliferation." in: The Journal of biological chemistry, Vol. 283, Issue 3, pp. 1428-36, (2008) (PubMed).
: "Sprouty2 binds Grb2 at two different proline-rich regions, and the mechanism of ERK inhibition is independent of this interaction." in: Cellular signalling, Vol. 19, Issue 11, pp. 2277-85, (2007) (PubMed).
: "Multiple-state reactions between the epidermal growth factor receptor and Grb2 as observed by using single-molecule analysis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 46, pp. 18013-8, (2007) (PubMed).
: "Angiotensin II type 2 receptor-dependent increases in nitric oxide synthase expression in the pulmonary endothelium is mediated via a G alpha i3/Ras/Raf/MAPK pathway." in: American journal of physiology. Cell physiology, Vol. 292, Issue 6, pp. C2185-96, (2007) (PubMed).
: "Use of signal specific receptor tyrosine kinase oncoproteins reveals that pathways downstream from Grb2 or Shc are sufficient for cell transformation and metastasis." in: Oncogene, Vol. 21, Issue 12, pp. 1800-11, (2002) (PubMed).
: "Downregulation of the Ras-mitogen-activated protein kinase pathway by the EphB2 receptor tyrosine kinase is required for ephrin-induced neurite retraction." in: Molecular and cellular biology, Vol. 21, Issue 21, pp. 7429-41, (2001) (PubMed).
: "Vav3 mediates receptor protein tyrosine kinase signaling, regulates GTPase activity, modulates cell morphology, and induces cell transformation." in: Molecular and cellular biology, Vol. 20, Issue 24, pp. 9212-24, (2000) (PubMed).
: "Association of Ash/Grb-2 with dynamin through the Src homology 3 domain." in: The Journal of biological chemistry, Vol. 269, Issue 8, pp. 5489-92, (1994) (PubMed).
Aliases for GRB2 抗体
growth factor receptor bound protein 2 (GRB2) 抗体growth factor receptor-bound protein 2 (grb2) 抗体
growth factor receptor bound protein 2 (Grb2) 抗体
growth factor receptor-bound protein 2b (grb2b) 抗体
AA408164 抗体
Ash 抗体
ASH 抗体
EGFRBP-GRB2 抗体
GRB2 抗体
grb2 抗体
Grb3-3 抗体
MST084 抗体
MSTP084 抗体
NCKAP2 抗体
wu:fb18e12 抗体
wu:fb34e06 抗体
zgc:73077 抗体
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