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GREM1 抗体

(Gremlin 1 (GREM1))
This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to relay the sonic hedgehog (SHH) signal from the polarizing region to the apical ectodermal ridge during limb bud outgrowth. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010].
GREM1 抗体  (AA 101-184) GREM1 抗体  (AA 101-184) GREM1 抗体 (AA 101-184) (ABIN687082)

GREM1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

GREM1 抗体  (C-Term) GREM1 抗体  (C-Term) GREM1 抗体 (C-Term) (ABIN545640)

GREM1 适用: 人, 小鼠 WB, IHC, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

GREM1 抗体  (C-Term) GREM1 抗体  (C-Term) GREM1 抗体 (C-Term) (ABIN390078)

GREM1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB2060 unconjugated

GREM1 抗体 by 适用

Find GREM1 抗体 for a variety of species such as anti-Human GREM1, anti-Mouse GREM1, anti-Rat GREM1. The species listed below are among those available. Click on a link to go to the corresponding products.

GREM1 抗体 by 应用范围

Find GREM1 抗体 validated for a specific application such as WB, ELISA, IHC, IF (cc). Some of the available applications are listed below. Click on a link to go to the corresponding products.

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Find GREM1 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

GREM1 抗体 by 抗原表位

Find GREM1 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

GREM1 抗体 by 克隆形成能力

Find available monoclonal or polyclonal GREM1 抗体. Click on a link to go to the corresponding products.

GREM1 抗体 by 克隆

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GREM1 抗体 by 标记

Find GREM1 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular GREM1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (1)
  • (5)
Cat. No. ABIN687082
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC, ELISA, IHC (p)
Validations
  • (3)
  • (5)
Cat. No. ABIN545640
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB
Validations
  • (9)
  • (7)
Cat. No. ABIN390078
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (5)
Cat. No. ABIN7434692
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (4)
Cat. No. ABIN7434695
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (3)
Cat. No. ABIN7426475
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (3)
Cat. No. ABIN7442135
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
  • (2)
Cat. No. ABIN565294
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA
Validations
  • (2)
Cat. No. ABIN7154448
Quantity 100 μg
Datasheet Datasheet
Reactivity Chicken
Application WB, IHC, IP, ICC
Validations
  • (2)
Cat. No. ABIN7437098
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (3)
Cat. No. ABIN5531272
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN565289
Quantity 50 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN7239959
Quantity 200 μL
Datasheet Datasheet
Reactivity Bat, Cow, Dog, Human, Monkey, Pig, Rabbit
Application IHC, ELISA, IHC (p)
Validations
  • (1)
Cat. No. ABIN208396
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6141382
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our GREM1 抗体

Staloch, Gao, Liu, Xu, Feng, Aronson, Falzon, Greeley, Rastellini, Chao, Hellmich, Cao, Ko: "Gremlin is a key pro-fibrogenic factor in chronic pancreatitis." in: Journal of molecular medicine (Berlin, Germany), (2015) (PubMed).

Droguett, Krall, Burgos, Valderrama, Carpio, Ardiles, Rodriguez-Diez, Kerr, Walz, Ruiz-Ortega, Egido, Mezzano: "Tubular overexpression of gremlin induces renal damage susceptibility in mice." in: PLoS ONE, Vol. 9, Issue 7, pp. e101879, (2014) (PubMed).

Wellbrock, Sheikhzadeh, Oliveira-Ferrer, Stamm, Hillebrand, Keyser, Klokow, Vohwinkel, Bonk, Otto, Streichert, Balabanov, Hagel, Rybczynski, Bentzien, Bokemeyer, von Kodolitsch, Fiedler: "Overexpression of Gremlin-1 in patients with Loeys-Dietz syndrome: implications on pathophysiology and early disease detection." in: PLoS ONE, Vol. 9, Issue 8, pp. e104742, (2014) (PubMed).

Ahn, Mercado, Laé, Ladanyi: "Identification of target genes of PAX3-FOXO1 in alveolar rhabdomyosarcoma." in: Oncology reports, Vol. 30, Issue 2, pp. 968-78, (2013) (PubMed).

Gelse, Ekici, Cipa, Swoboda, Carl, Olk, Hennig, Klinger: "Molecular differentiation between osteophytic and articular cartilage--clues for a transient and permanent chondrocyte phenotype." in: Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society, Vol. 20, Issue 2, pp. 162-71, (2012) (PubMed).

Jara, Chacón, Burgos, Droguett, Valdivieso, Ortiz, Troncoso, Mezzano: "Expression of gremlin, a bone morphogenetic protein antagonist,is associated with vascular calcification in uraemia." in: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, Vol. 24, Issue 4, pp. 1121-9, (2009) (PubMed).

Sha, Zhang, Zhang, Wan, Zhao, Li, Lang: "Elevated levels of gremlin-1 in eutopic endometrium and peripheral serum in patients with endometriosis." in: Fertility and sterility, Vol. 91, Issue 2, pp. 350-8, (2009) (PubMed).

Carvajal, Droguett, Burgos, Aros, Ardiles, Flores, Carpio, Ruiz-Ortega, Egido, Mezzano: "Gremlin: a novel mediator of epithelial mesenchymal transition and fibrosis in chronic allograft nephropathy." in: Transplantation proceedings, Vol. 40, Issue 3, pp. 734-9, (2008) (PubMed).

Krampert, Heldin, Heuchel: "A gain-of-function mutation in the PDGFR-beta alters the kinetics of injury response in liver and skin." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 88, Issue 11, pp. 1204-14, (2008) (PubMed).

Dudas, Mansuroglu, Batusic, Ramadori: "Thy-1 is expressed in myofibroblasts but not found in hepatic stellate cells following liver injury." in: Histochemistry and cell biology, Vol. 131, Issue 1, pp. 115-27, (2008) (PubMed).

Aliases for GREM1 抗体

gremlin 1a, DAN family BMP antagonist (grem1a) 抗体
gremlin 1, DAN family BMP antagonist (GREM1) 抗体
gremlin 1 (LOC662541) 抗体
gremlin 1, DAN family BMP antagonist (grem1) 抗体
gremlin 1, DAN family BMP antagonist (Grem1) 抗体
gremlin 1, DAN family BMP antagonist L homeolog (grem1.L) 抗体
Cktsf1b1 抗体
CKTSF1B1 抗体
cktsf1b1 抗体
dand2 抗体
DAND2 抗体
drm 抗体
Drm 抗体
DRM 抗体
Grem 抗体
grem1 抗体
GREM1 抗体
gremlin 抗体
GREMLIN 抗体
gremlin-1 抗体
ihg-2 抗体
IHG-2 抗体
ld 抗体
MGC136702 抗体
pig2 抗体
zgc:136702 抗体
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