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抗Human SLC19A1 抗体:
抗Mouse (Murine) SLC19A1 抗体:
抗Rat (Rattus) SLC19A1 抗体:
Human Polyclonal SLC19A1 Primary Antibody for IHC, WB - ABIN2781749
Payton, Liu, Ge, Matherly: Transcriptional regulation of the human reduced folate carrier A1/A2 promoter: Identification of critical roles for the USF and GATA families of transcription factors. in Biochimica et biophysica acta 2005
Show all 3 Pubmed References
miR (显示 MLXIP 抗体)-595 acts as a phenotypic regulator of methotrexate sensitivity in CEM/C1 cells by targeting SLC19A1.
RFC, IL15 and VDR germline variants are associated with minimal residual disease in pediatric B-cell precursor ALL
We identified eight novel variants in SLC19A1 and twelve novel variants in FOLR1 (显示 FOLR1 抗体), FOLR2 (显示 FOLR2 抗体), and FOLR3 (显示 FOLR3 抗体). Pathogenic variants include c.1265delG in SLC19A1 resulting in an early stop codon, four large insertion deletion variants in FOLR3 (显示 FOLR3 抗体), and a stop_gain variant in FOLR3 (显示 FOLR3 抗体)
Reduced SLC19A1 expression in human adipocytes induces DNA hypermethylation, resulting in increased expression of specific proinflammatory genes, including CCL2 (显示 CCL2 抗体). This constitutes an epigenetic mechanism that might link dysfunctional adipocytes to white adipose tissue inflammation and Insulin (显示 INS 抗体) resistance.
data suggested that the RFC1 (显示 RFC1 抗体) A80G G allele was an APOE (显示 APOE 抗体) 4-independent risk factor for late-onset Alzheimer's disease (AD
MTHFR (显示 MTHFR 抗体) 677C/T and RFC1 (显示 RFC1 抗体) 80G/A polymorphisms may serve as predictors of toxicity during maintenance chemotherapy in childhood acute lymphoblastic leukemia or lymphoma.
Neonatal RFC1 (显示 RFC1 抗体) polymorphism influenced total homocysteinein neonates
There was an association between RFC1 (显示 RFC1 抗体) A80G variant and the risk of nonsymdromic cleft lip with or without palate.
the G80A mutation in the RFC1 (显示 RFC1 抗体) gene is associated with a greater risk for sporadic breast cancer and oxidative DNA damage
We demonstrated no difference in tHcy, folates, vitamin B12 (显示 NDUFB3 抗体) levels and allelic frequencies of C677T and G80A polymorphisms in MTHFR (显示 MTHFR 抗体) and RFC (显示 RFC1 抗体) genes between obese and no obese Tunisian children.
The mRNAs encoding Folr2 and the intestinal folate transporter Slc46a1 were not detected in 2-cel embryos and blastocysts.
Interleukin-6 (显示 IL6 抗体) regulated the efficacy of methotrexate by decreasing the expression of SLC19A1.
First evidence of RFC expression in rapidly dividing cells of developing neural tube, craniofacial region, limb buds and heart duggests that these regions may be particularly susceptible to folate deficiency.
Inactivation of RFC1 (显示 RFC1 抗体) impacts the expression of several ligands and interacting proteins in the cubilin (显示 CUBN 抗体)-amnionless (显示 AMN 抗体)-megalin (显示 LRP2 抗体) complex that are involved in the maternal-fetal transport of folate and other nutrients.
Intestinal folate uptake process undergoes differentiation-dependent regulation and that this regulation is mediated via changes in the level of expression of both the RFC and PCFT (显示 SLC46A1 抗体).
The membrane protein encoded by this gene is a transporter of folate and is involved in the regulation of intracellular concentrations of folate. Three transcript variants encoding different isoforms have been found for this gene.
solute carrier family 19 (folate transporter), member 1
, folate transporter 1
, intestinal folate carrier 1
, placental folate transporter
, reduced folate carrier protein
, solute carrier family 19 member 1
, intestinal folate carrier protein
, reduced folate carrier 1
, solute carrier family 19 (sodium/hydrogen exchanger), member 1
, methotrexate carrier 1
, methotrexate carrier 2
, methotrexate carrier 5
, methotrexate carrier 6
, solute carrier family 19, member 1
, 58 kDa hydrophobic protein
, Folate carrier protein
, Methotrexate uptake protein
, Solute carrier family 19 member 1