SLC19A1 抗体 (N-Term)
(2 references)-
- 抗原 See all SLC19A1 抗体
- SLC19A1 (Solute Carrier Family 19 (Folate Transporter), Member 1 (SLC19A1))
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抗原表位
- N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SLC19A1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- MVPSSPAVEK QVPVEPGPDP ELRSWRHLVC YLCFYGFMAQ IRPGESFITP
- 预测反应
- Human: 100%
- 产品特性
- This is a rabbit polyclonal antibody against SLC19A1. It was validated on Western Blot and immunohistochemistry.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human SLC19A1
- Top Product
- Discover our top product SLC19A1 Primary Antibody
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anti-Solute Carrier Family 19 (Folate Transporter), Member 1 (SLC19A1) antibody
SLC19A1 适用: 小鼠, 人, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 19 (Folate Transporter), Member 1 (SLC19A1) (6th Cytoplasmic Loop), (AA 412-426) antibodySLC19A1 适用: 小鼠, 人, 大鼠 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 19 (Folate Transporter), Member 1 (SLC19A1) (N-Term) antibodySLC19A1 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 19 (Folate Transporter), Member 1 (SLC19A1) (AA 101-200) antibodySLC19A1 适用: 小鼠 WB, IF (cc), IF (p), ELISA, IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 19 (Folate Transporter), Member 1 (SLC19A1) (AA 452-591) antibodySLC19A1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 19 (Folate Transporter), Member 1 (SLC19A1) (AA 202-231), (Middle Region) antibodySLC19A1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 591 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "The antiepileptic drugs phenobarbital and carbamazepine reduce transport of methotrexate in rat choroid plexus by down-regulation of the reduced folate carrier." in: Molecular pharmacology, Vol. 80, Issue 4, pp. 621-9, (2011) (PubMed).
: "Pralatrexate is synergistic with the proteasome inhibitor bortezomib in in vitro and in vivo models of T-cell lymphoid malignancies." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 16, Issue 14, pp. 3648-58, (2010) (PubMed).
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: "The antiepileptic drugs phenobarbital and carbamazepine reduce transport of methotrexate in rat choroid plexus by down-regulation of the reduced folate carrier." in: Molecular pharmacology, Vol. 80, Issue 4, pp. 621-9, (2011) (PubMed).
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- 抗原
- SLC19A1 (Solute Carrier Family 19 (Folate Transporter), Member 1 (SLC19A1))
- 别名
- SLC19A1 (SLC19A1 产品)
- 别名
- A1 antibody, MHCBFB antibody, PO-GA antibody, RECC1 antibody, RFC antibody, RFC140 antibody, CHMD antibody, FOLT antibody, IFC1 antibody, REFC antibody, RFC1 antibody, LOC100226745 antibody, AI323572 antibody, RFC-1 antibody, MTX1 antibody, XRFC antibody, chmd antibody, folt antibody, ifc1 antibody, refc antibody, rfc1 antibody, slc19a1 antibody, replication factor C subunit 1 antibody, solute carrier family 19 member 1 antibody, folate transporter 1 antibody, solute carrier family 19 (folate transporter), member 1 antibody, solute carrier family 19 (folate transporter), member 1 L homeolog antibody, RFC1 antibody, SLC19A1 antibody, LOC100226745 antibody, Slc19a1 antibody, slc19a1.L antibody
- 背景
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Transport of folate compounds into mammalian cells can occur via receptor-mediated or carrier-mediated mechanisms. A functional coordination between these 2 mechanisms has been proposed to be the method of folate uptake in certain cell types. Methotrexate (MTX) is an antifolate chemotherapeutic agent that is actively transported by the carrier-mediated uptake system. SLC19A1 plays a role in maintaining intracellular concentrations of folate.Transport of folate compounds into mammalian cells can occur via receptor-mediated (see MIM 136430) or carrier-mediated mechanisms. A functional coordination between these 2 mechanisms has been proposed to be the method of folate uptake in certain cell types. Methotrexate (MTX) is an antifolate chemotherapeutic agent that is actively transported by the carrier-mediated uptake system. RFC1 plays a role in maintaining intracellular concentrations of folate.[supplied by OMIM].
Alias Symbols: CHMD, FOLT, IFC1, REFC, RFC1
Protein Interaction Partner: UBC,
Protein Size: 591 - 分子量
- 65 kDa
- 基因ID
- 6573
- NCBI登录号
- NM_194255, NP_919231
- UniProt
- P41440
- 途径
- Dicarboxylic Acid Transport
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