CLCN3 抗体
(Chloride Channel 3 (CLCN3))
This gene encodes a member of the voltage-gated chloride channel (ClC) family. The encoded protein is present in all cell types and localized in plasma membranes and in intracellular vesicles. It is a multi-pass membrane protein which contains a ClC domain and two additional C-terminal CBS (cystathionine beta-synthase) domains. The ClC domain catalyzes the selective flow of Cl- ions across cell membranes, and the CBS domain may have a regulatory function. This protein plays a role in both acidification and transmitter loading of GABAergic synaptic vesicles, and in smooth muscle cell activation and neointima formation. This protein is required for lysophosphatidic acid (LPA)-activated Cl- current activity and fibroblast-to-myofibroblast differentiation. The protein activity is regulated by Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) in glioma cells. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| CLCN3 抗体 (Cytosolic, N-Term) (FL550) | 大鼠 | 小鼠 Monoclonal |
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| CLCN3 抗体 (C-Term, Intracellular) | 人, 大鼠, 小鼠 | 兔 Polyclonal |
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| CLCN3 抗体 (Center) | 人, 大鼠, 小鼠 | 兔 Polyclonal |
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| CLCN3 抗体 (AA 293-752) | 人, 大鼠 | 兔 Polyclonal |
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| CLCN3 抗体 (N-Term) | 大鼠 | 小鼠 Monoclonal |
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Primary Antibody
- IHC (Immunohistochemistry: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
KO 验证
- 质量等级
- KO Validated
- 适用
- 大鼠
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- N258-5
- 标记
- FL550
- 抗体亚型
- IgG1
- 抗原表位
- AA 98-115, Cytosolic, N-Term
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- IC (Immunochromatography: 所列应用)
- IP (Immunoprecipitation: 所列应用)
KO 验证
- 质量等级
- Carrier-free, KO Validated
- 适用
- 人, 大鼠, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 592-661, C-Term, Intracellular
Primary Antibody
- WB (Western Blotting: 所列应用)
- 适用
- 人, 大鼠, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- Center
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- ELISA (ELISA: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- 适用
- 人, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 293-752
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- IC (Immunochromatography: 所列应用)
- 适用
- 大鼠
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- S258-5
- 标记
- unconjugated
- 抗体亚型
- IgG1
- 抗原表位
- N-Term
Latest Publications for our CLCN3 抗体
: "CAPS1 effects on intragranular pH and regulation of BDNF release from secretory granules in hippocampal neurons." in: Journal of cell science, Vol. 129, Issue 7, pp. 1378-90, (2016) (PubMed).
: "Novel CLC3 transcript variants in blood eosinophils and increased CLC3 expression in nasal lavage and blood eosinophils of asthmatics." in: Immunity, inflammation and disease, Vol. 2, Issue 4, pp. 205-13, (2015) (PubMed).
: "Chloride-hydrogen antiporters ClC-3 and ClC-5 drive osteoblast mineralization and regulate fine-structure bone patterning in vitro." in: Physiological reports, Vol. 3, Issue 11, (2015) (PubMed).
: "Calcium entry via TRPC1 channels activates chloride currents in human glioma cells." in: Cell calcium, Vol. 53, Issue 3, pp. 187-94, (2013) (PubMed).
: "A quantitative assay for lysosomal acidification rates in human osteoclasts." in: Assay and drug development technologies, Vol. 9, Issue 2, pp. 157-64, (2011) (PubMed).
: "Expression and localization of CLC chloride transport proteins in the avian retina." in: PLoS ONE, Vol. 6, Issue 3, pp. e17647, (2011) (PubMed).
: "Novel CLC3 transcript variants in blood eosinophils and increased CLC3 expression in nasal lavage and blood eosinophils of asthmatics." in: Immunity, inflammation and disease, Vol. 2, Issue 4, pp. 205-13, (2015) (PubMed).
: "Chloride-hydrogen antiporters ClC-3 and ClC-5 drive osteoblast mineralization and regulate fine-structure bone patterning in vitro." in: Physiological reports, Vol. 3, Issue 11, (2015) (PubMed).
: "Calcium entry via TRPC1 channels activates chloride currents in human glioma cells." in: Cell calcium, Vol. 53, Issue 3, pp. 187-94, (2013) (PubMed).
: "A quantitative assay for lysosomal acidification rates in human osteoclasts." in: Assay and drug development technologies, Vol. 9, Issue 2, pp. 157-64, (2011) (PubMed).
: "Expression and localization of CLC chloride transport proteins in the avian retina." in: PLoS ONE, Vol. 6, Issue 3, pp. e17647, (2011) (PubMed).
Aliases for CLCN3 抗体
chloride voltage-gated channel 3 (CLCN3) 抗体chloride voltage-gated channel 3 (Clcn3) 抗体
chloride channel, voltage-sensitive 3 (Clcn3) 抗体
chloride channel 3 (clcn3) 抗体
chloride channel protein 3 (PTRG_03131) 抗体
chloride channel protein 3 (BDBG_05668) 抗体
chloride channel protein 3 (MCYG_04420) 抗体
chloride channel, voltage-sensitive 3 (clcn3) 抗体
chloride channel, voltage-sensitive 3 S homeolog (clcn3.S) 抗体
ClC-3 抗体
clc-3 抗体
CLC3 抗体
Clc3 抗体
clc3 抗体
CLCN3 抗体
fb78c02 抗体
wu:fb78c02 抗体
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