CLDN8 抗体
(Claudin 8 (CLDN8))
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This protein plays important roles in the paracellular cation barrier of the distal renal tubule, and in the paracellular barrier to prevent sodium back-leakage in distal colon. Differential expression of this gene has been observed in colorectal carcinoma and renal cell tumors, and along with claudin-7, is an immunohistochemical marker for the differential diagnosis of chromophobe renal cell carcinoma and renal oncocytoma.[provided by RefSeq, May 2010].
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Latest Publications for our CLDN8 抗体
: "Gluten-induced symptoms in diarrhea-predominant irritable bowel syndrome are associated with increased myosin light chain kinase activity and claudin-15 expression." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 97, Issue 1, pp. 14-23, (2016) (PubMed).
: "Claudin 8 Contributes to Malignant Proliferation in Human Osteosarcoma U2OS Cells." in: Cancer biotherapy & radiopharmaceuticals, Vol. 30, Issue 9, pp. 400-4, (2015) (PubMed).
: "Claudin 8 Contributes to Malignant Proliferation in Human Osteosarcoma U2OS Cells." in: Cancer biotherapy & radiopharmaceuticals, Vol. 30, Issue 9, pp. 400-4, (2015) (PubMed).
Aliases for CLDN8 抗体
claudin 8 (CLDN8) 抗体claudin 8 (cldn8) 抗体
claudin 8 (Cldn8) 抗体
AI648025 抗体
CLDN8 抗体
wu:fa01e05 抗体
zgc:91900 抗体
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