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CYP1A1 抗体

CYP1A1 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 6G5 unconjugated
产品编号 ABIN969511
发货至: 中国
  • 抗原 See all CYP1A1 抗体
    CYP1A1 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 1 (CYP1A1))
    适用
    • 53
    • 25
    • 14
    • 4
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    • 3
    • 3
    • 3
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    • 1
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    • 1
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    宿主
    • 37
    • 23
    • 1
    小鼠
    克隆类型
    • 40
    • 21
    单克隆
    标记
    • 39
    • 4
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    • 2
    • 1
    • 1
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    This CYP1A1 antibody is un-conjugated
    应用范围
    • 47
    • 26
    • 16
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of human CYP1A1 expressed in E. coli.
    克隆位点
    6G5
    亚型
    IgG1
    Top Product
    Discover our top product CYP1A1 Primary Antibody
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • Canova, Hashibe, Simonato, Nelis, Metspalu, Lagiou, Trichopoulos, Ahrens, Pigeot, Merletti, Richiardi, Talamini, Barzan, Macfarlane, Macfarlane, Holcátová, Bencko, Benhamou, Bouchardy, Kjaerheim et al.: "Genetic associations of 115 polymorphisms with cancers of the upper aerodigestive tract across 10 European countries: the ARCAGE project. ..." in: Cancer research, Vol. 69, Issue 7, pp. 2956-65, (2009) (PubMed).

    Breuer, Schmidt, Schuphan: "Utility of Nicotiana tabacum cell suspension cultures expressing human CYP1A1, CYP1A2 and CYP3A4 to study the oxidative metabolism of the herbicide 14C-fluometuron." in: Drug metabolism letters, Vol. 3, Issue 1, pp. 18-27, (2009) (PubMed).

  • 抗原
    CYP1A1 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 1 (CYP1A1))
    别名
    CYP1A1 (CYP1A1 产品)
    别名
    AHH antibody, AHRR antibody, CP11 antibody, CYP1 antibody, P1-450 antibody, P450-C antibody, P450DX antibody, Cyp1a2 antibody, P450-1 antibody, cyp1a1 antibody, CYP1A1 antibody, CYPIA1 antibody, Cyp45c antibody, Cypc45c antibody, P-450MC antibody, wu:fb63b04 antibody, zfCYP1A antibody, zgc:109747 antibody, ahh antibody, ahrr antibody, cp11 antibody, cyp1 antibody, cyp1a antibody, p1-450 antibody, p450-c antibody, p450dx antibody, cytochrome P450 family 1 subfamily A member 1 antibody, cytochrome P450 1A1 antibody, cytochrome P450, family 1, subfamily a, polypeptide 1 antibody, cytochrome P450, family 1, subfamily A, polypeptide 1 antibody, cytochrome P450 family 1 subfamily D polypeptide 1 antibody, cytochrome P4501A1 antibody, polycyclic hydrocarbon-inducible cytochrome P450c antibody, cytochrome P450, family 1, subfamily A antibody, cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 1 antibody, cytochrome P450 family 1 subfamily A member 1 L homeolog antibody, CYP1A1 antibody, CpipJ_CPIJ010542 antibody, Cyp1a1 antibody, cyp1d1 antibody, LOC100328613 antibody, cyp1a antibody, LOC102129994 antibody, cyp1a1.L antibody
    背景

    Description: This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown, however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15.

    Aliases: AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX

    分子量
    58 kDa
    基因ID
    1543
    HGNC
    1543
    途径
    Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha
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