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SLC22A1 抗体

SLC22A1 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 2C5 unconjugated
产品编号 ABIN969400
发货至: 中国
  • 抗原 See all SLC22A1 抗体
    SLC22A1 (Solute Carrier Family 22 (Organic Cation Transporter), Member 1 (SLC22A1))
    适用
    • 47
    • 9
    • 8
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    宿主
    • 40
    • 8
    • 1
    小鼠
    克隆类型
    • 41
    • 8
    单克隆
    标记
    • 22
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This SLC22A1 antibody is un-conjugated
    应用范围
    • 31
    • 23
    • 17
    • 2
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS)
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of human SLC22A1 expressed in E. coli.
    克隆位点
    2C5
    亚型
    IgG1
    Top Product
    Discover our top product SLC22A1 Primary Antibody
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • Zach, Krieger, Foedermayr, Zellhofer, Lutz: "OCT1 (SLC22A1) R61C polymorphism and response to imatinib treatment in chronic myeloid leukemia patients." in: Leukemia & lymphoma, Vol. 49, Issue 11, pp. 2222-3, (2008) (PubMed).

    Hirayama, Watanabe, Nakashima, Nanbu, Hamada, Kuniyasu, Nakayama, Kawaguchi, Saito: "Constitutive overexpression of P-glycoprotein, rather than breast cancer resistance protein or organic cation transporter 1, contributes to acquisition of imatinib-resistance in K562 cells." in: Pharmaceutical research, Vol. 25, Issue 4, pp. 827-35, (2008) (PubMed).

    Giannoudis, Davies, Lucas, Harris, Pirmohamed, Clark: "Effective dasatinib uptake may occur without human organic cation transporter 1 (hOCT1): implications for the treatment of imatinib-resistant chronic myeloid leukemia." in: Blood, Vol. 112, Issue 8, pp. 3348-54, (2008) (PubMed).

  • 抗原
    SLC22A1 (Solute Carrier Family 22 (Organic Cation Transporter), Member 1 (SLC22A1))
    别名
    SLC22A1 (SLC22A1 产品)
    别名
    SLC22A1 antibody, OCT1 antibody, HOCT1 antibody, oct1_cds antibody, Lx1 antibody, Oct1 antibody, Orct antibody, Orct1 antibody, Roct1 antibody, SLC22A2 antibody, solute carrier family 22 member 1 antibody, solute carrier family 22 (organic cation transporter), member 1 antibody, solute carrier family 22 member 2-like antibody, SLC22A1 antibody, Slc22a1 antibody, LOC421584 antibody
    背景

    Description: Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. Tissue specificity: Widely expressed with high level in liver.

    Aliases: OCT1, HOCT1, oct1_cds, SLC22A1

    分子量
    61.2 kDa
    基因ID
    6580
    HGNC
    6580
    途径
    Hormone Transport
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