电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

SLC22A1 抗体 (N-Term)

SLC22A1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6263799
发货至: 中国
  • 抗原 See all SLC22A1 抗体
    SLC22A1 (Solute Carrier Family 22 (Organic Cation Transporter), Member 1 (SLC22A1))
    抗原表位
    • 13
    • 8
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 47
    • 9
    • 8
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    宿主
    • 39
    • 9
    • 1
    克隆类型
    • 40
    • 9
    多克隆
    标记
    • 22
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This SLC22A1 antibody is un-conjugated
    应用范围
    • 31
    • 23
    • 17
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    特异性
    OCT1 Antibody detects endogenous levels of total OCT1.
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human OCT1, corresponding to a region within N-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product SLC22A1 Primary Antibody
  • 应用备注
    WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    SLC22A1 (Solute Carrier Family 22 (Organic Cation Transporter), Member 1 (SLC22A1))
    别名
    SLC22A1 (SLC22A1 产品)
    别名
    SLC22A1 antibody, OCT1 antibody, HOCT1 antibody, oct1_cds antibody, Lx1 antibody, Oct1 antibody, Orct antibody, Orct1 antibody, Roct1 antibody, SLC22A2 antibody, solute carrier family 22 member 1 antibody, solute carrier family 22 (organic cation transporter), member 1 antibody, solute carrier family 22 member 2-like antibody, SLC22A1 antibody, Slc22a1 antibody, LOC421584 antibody
    背景

    Description: Translocates a broad array of organic cations with various structures and molecular weights including the model compounds 1-methyl-4-phenylpyridinium (MPP), tetraethylammonium (TEA), N-1-methylnicotinamide (NMN), 4-(4-(dimethylamino)styryl)-N-methylpyridinium (ASP), the endogenous compounds choline, guanidine, histamine, epinephrine, adrenaline, noradrenaline and dopamine, and the drugs quinine, and metformin. The transport of organic cations is inhibited by a broad array of compounds like tetramethylammonium (TMA), cocaine, lidocaine, NMDA receptor antagonists, atropine, prazosin, cimetidine, TEA and NMN, guanidine, cimetidine, choline, procainamide, quinine, tetrabutylammonium, and tetrapentylammonium. Translocates organic cations in an electrogenic and  pH -independent manner. Translocates organic cations across the plasma membrane in both directions. Transports the polyamines spermine and spermidine. Transports pramipexole across the basolateral membrane of the proximal tubular epithelial cells. The choline transport is activated by MMTS. Regulated by various intracellular signaling pathways including inhibition by protein kinase A activation, and endogenously activation by the calmodulin complex, the calmodulin-dependent kinase II and LCK tyrosine kinase.

    Gene: SLC22A1

    分子量
    61 kDa
    基因ID
    6580
    UniProt
    O15245
    途径
    Hormone Transport
You are here:
客服