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CD73 抗体

NT5E 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 1D7 unconjugated
产品编号 ABIN969322
发货至: 中国
  • 抗原 See all CD73 (NT5E) 抗体
    CD73 (NT5E) (5'-Nucleotidase, Ecto (CD73) (NT5E))
    适用
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    宿主
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    小鼠
    克隆类型
    • 73
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    单克隆
    标记
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    This CD73 antibody is un-conjugated
    应用范围
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    Immunohistochemistry (IHC), ELISA
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of NT5E expressed in E. coli.
    克隆位点
    1D7
    亚型
    IgG1
    Top Product
    Discover our top product NT5E Primary Antibody
  • 应用备注
    ELISA: 1:10000, IHC: 1:200 - 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • Zhou, Zhi, Zhou, Chen, Zhao, Shao, Ou, Yin: "Effects of ecto-5'-nucleotidase on human breast cancer cell growth in vitro and in vivo." in: Oncology reports, Vol. 17, Issue 6, pp. 1341-6, (2007) (PubMed).

    Wink, Braganhol, Tamajusuku, Casali, Karl, Barreto-Chaves, Sarkis, Battastini: "Extracellular adenine nucleotides metabolism in astrocyte cultures from different brain regions." in: Neurochemistry international, Vol. 43, Issue 7, pp. 621-8, (2003) (PubMed).

  • 抗原
    CD73 (NT5E) (5'-Nucleotidase, Ecto (CD73) (NT5E))
    别名
    NT5E (NT5E 产品)
    别名
    CALJA antibody, CD73 antibody, E5NT antibody, NT antibody, NT5 antibody, NTE antibody, eN antibody, eNT antibody, zgc:63784 antibody, NT5E antibody, MGC114869 antibody, PSPTO2277 antibody, 2210401F01Rik antibody, AI447961 antibody, Nt5 antibody, 5'-nucleotidase ecto antibody, 5'-nucleotidase, ecto (CD73) antibody, 5'-nucleotidase antibody, 5' nucleotidase, ecto antibody, NT5E antibody, nt5e antibody, nt5e.S antibody, PSPTO_2277 antibody, CBU_1233 antibody, MCA1322 antibody, Nt5e antibody
    背景

    Description: 5'-nucleotidase, ecto (NT5E), also known as CD73 (Cluster of Differentiation 73). Ecto-5-prime-nucleotidase (5-prime-ribonucleotide phosphohydrolase, EC 3.1.3.5) catalyzes the conversion at neutral pH of purine 5-prime mononucleotides to nucleosides, the preferred substrate being AMP. The enzyme consists of a dimer of 2 identical 70-kD subunits bound by a glycosyl phosphatidyl inositol linkage to the external face of the plasma membrane. The enzyme is used as a marker of lymphocyte differentiation. Consequently, a deficiency of NT5 occurs in a variety of immunodeficiency diseases (e.g., see MIM 102700, MIM 300300). Other forms of 5-prime nucleotidase exist in the cytoplasm and lysosomes and can be distinguished from ecto-NT5 by their substrate affinities, requirement for divalent magnesium ion, activation by ATP, and inhibition by inorganic phosphate.

    Aliases: eN, NT5, CD73

    分子量
    70 kDa
    基因ID
    4907
    HGNC
    4907
    途径
    Synaptic Membrane, Ribonucleoside Biosynthetic Process
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