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HSP27 抗体

HSPB1 适用: 人, 大鼠 WB, IHC, ELISA, IF, FACS 宿主: 小鼠 Monoclonal 5D7 unconjugated
产品编号 ABIN966308
发货至: 中国
  • 抗原 See all HSP27 (HSPB1) 抗体
    HSP27 (HSPB1) (Heat Shock 27kDa Protein 1 (HSPB1))
    适用
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    人, 大鼠
    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This HSP27 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of human HSP27 expressed in E. Coli.
    克隆位点
    5D7
    亚型
    IgG1
    Top Product
    Discover our top product HSPB1 Primary Antibody
  • 应用备注
    Western Bloting: 1/500 - 1/2000.
    Immunohistochemistry: 1/200 - 1/1000.
    Immunofluorescence: 1/200 - 1/1000.
    Flow cytometry: 1/200 - 1/400.
    ELISA: Propose dilution 1/10000.
    Not yet tested in other applications.
    Determining optimal working dilutions by titration test.
    限制
    仅限研究用
  • 状态
    Liquid
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
  • Langer, Ott, Specht, Becker, Lordick, Burian, Herrmann, Schrattenholz, Cahill, Schwaiger, Hofler, Wester: "Protein expression profiling in esophageal adenocarcinoma patients indicates association of heat-shock protein 27 expression and chemotherapy response." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 14, Issue 24, pp. 8279-87, (2008) (PubMed).

    Wu, Liu, Zhang, Huang, Shen, Zhang, Jiang, Luo, Yin: "HSP27 regulates IL-1 stimulated IKK activation through interacting with TRAF6 and affecting its ubiquitination." in: Cellular signalling, Vol. 21, Issue 1, pp. 143-50, (2008) (PubMed).

  • 抗原
    HSP27 (HSPB1) (Heat Shock 27kDa Protein 1 (HSPB1))
    别名
    HSP27 (HSPB1 产品)
    别名
    CMT2F antibody, HMN2B antibody, HS.76067 antibody, HSP27 antibody, HSP28 antibody, Hsp25 antibody, SRP27 antibody, 27kDa antibody, Hsp27 antibody, cb153 antibody, cb660 antibody, hsp1 antibody, hsp25 antibody, hsp27 antibody, id:ibd2821 antibody, sb:cb660 antibody, zgc:103437 antibody, HSPB1 antibody, cmt2f antibody, hs.76067 antibody, hsp28 antibody, heat shock protein family B (small) member 1 antibody, heat shock protein 1 antibody, heat shock protein, alpha-crystallin-related, 1 antibody, heat shock protein family B (small) member 1 L homeolog antibody, HSPB1 antibody, Hspb1 antibody, hspb1 antibody, hspb1.L antibody
    背景
    The protein encoded by this gene is induced by environmental stress and developmental changes. The encoded protein is involved in stress resistance and actin organization and translocates from the cytoplasm to the nucleus upon stress induction. Defects in this gene are a cause of Charcot-Marie-Tooth disease type 2F (CMT2F) and distal hereditary motor neuropathy (dHMN).
    Tissue specificity: Detected in all tissues tested: skeletal muscle, heart, aorta, large intestine, small intestine, stomach, esophagus, bladder, adrenal gland, thyroid, pancreas, testis, adipose tissue, kidney, liver, spleen, cerebral cortex, blood serum and cerebrospinal fluid. Highest levels are found in the heart and in tissues composed of striated and smooth muscle.
    Synonyms: CMT2F, HMN2B, HSP27, HSP28, Hsp25, SRP27, HS.76067, DKFZp586P1322, HSPB1
    分子量
    27kDa
    基因ID
    3315
    途径
    MAPK Pathway, Regulation of Actin Filament Polymerization, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of intrinsic apoptotic Signaling, VEGF Signaling
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