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CHEK1 抗体

This anti-CHEK1 antibody is a 单克隆 antibody detecting CHEK1 in WB 和 ELISA. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN965882
发货至: 中国

Quick Overview for CHEK1 抗体 (ABIN965882)

抗原

See all CHEK1 抗体
CHEK1 (Checkpoint Kinase 1 (CHEK1))

适用

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克隆类型

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单克隆

标记

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This CHEK1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 特异性

    Ni-NTA purified recombinant protein CHK1 expressed in E. Coli strain M15.

    纯化方法

    Antibodies are purified by protein G affinity chromatography.

    亚型

    IgG1
  • 应用备注

    Western Blot: Dilution 1: 2,00- 1: 1,000
    ELISA: Propose dilution 1: 10,000.
    Determining optimal working dilutions by titration test.

    限制

    仅限研究用
  • 储存条件

    -20 °C
  • OConnell, Raleigh, Verkade, Nurse: "Chk1 is a wee1 kinase in the G2 DNA damage checkpoint inhibiting cdc2 by Y15 phosphorylation." in: The EMBO journal, Vol. 16, Issue 3, pp. 545-54, (1997) (PubMed).

  • 抗原

    CHEK1 (Checkpoint Kinase 1 (CHEK1))

    别名

    CHK1

    背景

    Active recombinant full length human CHK1 containing an Nterminal GST tag. This protein has an apparent molecular weight of ~82kDa. CHK1 appears to function downstream of several of the known fission yeast checkpoint gene products, including that encoded by rad3+, a gene with sequence similarity to the ATM gene mutated in patients with ataxia telangiectasia.

    途径

    p53 Pathway, Apoptosis, Cell Division Cycle, DNA Damage Repair
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