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- 抗原 See all SETD2 抗体
- SETD2 (SET Domain Containing 2 (SETD2))
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抗原表位
- Internal Region
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适用
- 人, 小鼠
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宿主
- 山羊
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克隆类型
- 多克隆
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标记
- This SETD2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 序列
- C-ERDPDKQTQN KE
- 特异性
- This antibody recognizes HYPB / SETD2 (internal region).
- 交叉反应 （详细）
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Species reactivity (expected):Human.
Species reactivity (tested):Mouse. - 纯化方法
- Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide
- 免疫原
- Peptide with sequence from the internal region of the protein sequence according to NP_054878.3. Genename: SETD2
- Top Product
- Discover our top product SETD2 Primary Antibody
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anti-SET Domain Containing 2 (SETD2) (AA 803-1103) antibody
SETD2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-SET Domain Containing 2 (SETD2) (AA 2054-2245) antibodySETD2 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 4G11E6 unconjugated
anti-SET Domain Containing 2 (SETD2) (Internal Region) antibodyVerified SETD2 适用: 人 ELISA, FACS 宿主: 山羊 Polyclonal unconjugated
anti-SET Domain Containing 2 (SETD2) (N-Term) antibodySETD2 适用: 人, 小鼠, 大鼠, 犬, 马, Cow WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-SET Domain Containing 2 (SETD2) (AA 21-50), (N-Term) antibodySETD2 适用: 人 IHC (p) 宿主: 兔 Polyclonal RB2780 unconjugated
anti-SET Domain Containing 2 (SETD2) antibodySETD2 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-SET Domain Containing 2 (SETD2) (AA 323-372) antibodySETD2 适用: 人, 小鼠, 大鼠, 犬, 马, Cow WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Tris buffered saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- SETD2 (SET Domain Containing 2 (SETD2))
- 别名
- SETD2 / HIF1 (SETD2 产品)
- 别名
- Kif9 antibody, HBP231 antibody, HIF-1 antibody, HIP-1 antibody, HYPB antibody, KMT3A antibody, SET2 antibody, p231HBP antibody, SET domain containing 2 antibody, Setd2 antibody, SETD2 antibody
- 背景
- SET2 is a Histone methyltransferase that methylates 'Lys-36' of Histone H3. H3 'Lys-36' methylation represents a specific tag for epigenetic transcriptional activation. This protein probably plays a role in chromatin structure modulation during elongation via its interaction with hyperphosphorylated POLR2A. SET2 binds DNA at promoters, and may act as a transcription activator. SET2 binds to the promoters of adenovirus 12 E1A gene in case of infection, possibly leading to regulate its expression. Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. SET2 belongs to a class of huntingtin interacting proteins characterized by WW motifs.Synonyms: HIF-1, HIP-1, HIP1, HYPB, Histone-lysine N-methyltransferase SETD2, Huntingtin yeast partner B, Huntingtin-interacting protein 1, Huntingtin-interacting protein B, KIAA1732, KMT3A, Lysine N-methyltransferase 3A, SET domain-containing protein 2, SET2, p231HBP
- 基因ID
- 29072
- NCBI登录号
- NP_054878
- 途径
- Tube Formation
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