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CTLA4 抗体

CTLA4 适用: 人 FACS 宿主: 小鼠 Monoclonal A3-4H2-H12 unconjugated
产品编号 ABIN951194
发货至: 中国
  • 抗原 See all CTLA4 抗体
    CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
    适用
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    宿主
    • 58
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    小鼠
    克隆类型
    • 72
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    单克隆
    标记
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    This CTLA4 antibody is un-conjugated
    应用范围
    • 77
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    Flow Cytometry (FACS)
    特异性
    Human CTLA-4 (also known as Cytotoxic T lymphocyte-associated antigen-4, CD152) is a structural homologue of T cell co-stimulatory receptor CD28. CTLA-4 binds to the same ligands (CD80 and CD86) as CD28 but with much higher avidity. It is expressed at very low levels on the cell surface of activated T cells, and is found primarily in the post-Golgi or endosomal compartments of the cell. There is a high degree of overall homology between human and mouse CTLA-4 (>70 %), and the cytoplasmic domains of the human, mouse and rabbit sequences are completely conserved. CD152 antibodies have shown both stimulatory and negative regulatory roles in functional experiments.
    纯化方法
    Affinity chromatography on Protein G
    免疫原
    Activated T cells Donor: Balb/c mouse Fusion Partner: SP 2/0 myeloma
    克隆位点
    A3-4H2-H12
    亚型
    IgG2a
    Top Product
    Discover our top product CTLA4 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1,0 mg/mL
    缓冲液
    PBS containing 0.02 % sodium azide (NaN3) as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
    别名
    CD152 / CTLA4 (CTLA4 产品)
    别名
    CTLA-4 antibody, CTLA4 antibody, CD152 antibody, Cd152 antibody, Ctla-4 antibody, Ly-56 antibody, CD antibody, CELIAC3 antibody, GRD4 antibody, GSE antibody, IDDM12 antibody, sCTLA4 antibody, cytotoxic T-lymphocyte associated protein 4 antibody, cytotoxic T-lymphocyte-associated protein 4 antibody, CTLA4 antibody, Ctla4 antibody
    背景
    Synonyms: CTLA-4, Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4
    基因ID
    1493
    NCBI登录号
    NP_001032720
    UniProt
    P16410
    途径
    Cancer Immune Checkpoints
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