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CTLA4 抗体 (AA 75-170)

CTLA4 适用: 人, 小鼠, 大鼠 FACS, WB, ELISA, IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1714514
发货至: 中国
  • 抗原 See all CTLA4 抗体
    CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
    抗原表位
    • 15
    • 12
    • 6
    • 6
    • 6
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 75-170
    适用
    • 90
    • 59
    • 34
    • 5
    • 4
    人, 小鼠, 大鼠
    宿主
    • 61
    • 47
    • 13
    • 10
    • 1
    • 1
    克隆类型
    • 77
    • 53
    • 2
    多克隆
    标记
    • 63
    • 15
    • 13
    • 12
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CTLA4 antibody is un-conjugated
    应用范围
    • 79
    • 64
    • 51
    • 33
    • 17
    • 17
    • 14
    • 12
    • 10
    • 7
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    人, 小鼠, 大鼠
    预测反应
    Dog,Cow,Sheep,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human CTLA-4/CD152
    亚型
    IgG
    Top Product
    Discover our top product CTLA4 Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • Schlößer, Drebber, Kloth, Thelen, Rothschild, Haase, Garcia-Marquez, Wennhold, Berlth, Urbanski, Alakus, Schauss, Shimabukuro-Vornhagen, Theurich, Warnecke-Ebertz, Stippel, Zippelius, Büttner, Hallek et al.: "Immune checkpoints programmed death 1 ligand 1 and cytotoxic T lymphocyte associated molecule 4 in gastric adenocarcinoma. ..." in: Oncoimmunology, Vol. 5, Issue 5, pp. e1100789, (2016) (PubMed).

    Tamaka, Seike, Hagiwara, Sato, Ohtsu: "Histamine suppresses regulatory T cells mediated by TGF-? in murine chronic allergic contact dermatitis." in: Experimental dermatology, Vol. 24, Issue 4, pp. 280-4, (2015) (PubMed).

  • 抗原
    CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
    别名
    CTLA4 (CTLA4 产品)
    别名
    CTLA-4 antibody, CTLA4 antibody, CD152 antibody, Cd152 antibody, Ctla-4 antibody, Ly-56 antibody, CD antibody, CELIAC3 antibody, GRD4 antibody, GSE antibody, IDDM12 antibody, sCTLA4 antibody, cytotoxic T-lymphocyte associated protein 4 antibody, cytotoxic T-lymphocyte-associated protein 4 antibody, CTLA4 antibody, Ctla4 antibody
    背景

    Synonyms: CD, GSE, GRD4, CD152, CTLA-4, IDDM12, CELIAC3, Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4, CTLA4

    Background: Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.

    基因ID
    1493
    UniProt
    P16410
    途径
    Cancer Immune Checkpoints
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