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CARD16 抗体 (N-Term)

CARD16 适用: 人 WB, FACS, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN951040
发货至: 中国
  • 抗原 See all CARD16 抗体
    CARD16 (Caspase Recruitment Domain Family, Member 16 (CARD16))
    抗原表位
    • 7
    • 5
    • 4
    • 1
    • 1
    • 1
    AA 44-73, N-Term
    适用
    宿主
    • 21
    • 4
    • 1
    克隆类型
    • 24
    • 2
    多克隆
    标记
    • 12
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CARD16 antibody is un-conjugated
    应用范围
    • 15
    • 13
    • 8
    • 4
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
    特异性
    This antibody reacts to COP1.
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography on Protein A
    免疫原
    KLH conjugated synthetic peptide between 44-73 amino acids from the N-terminal region of human COP1
    亚型
    Ig Fraction
    Top Product
    Discover our top product CARD16 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS, 0.09 % (W/V) sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    CARD16 (Caspase Recruitment Domain Family, Member 16 (CARD16))
    别名
    CARD16 / COP1 (CARD16 产品)
    别名
    COP antibody, COP1 antibody, PSEUDO-ICE antibody, caspase recruitment domain family member 16 antibody, CARD16 antibody
    背景
    Caspase inhibitor. Acts as a regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-interleukin-1 beta (IL1B) and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. Also induces NF-kappa-B activation during the pro-inflammatory cytokine response. Also able to inhibit CASP1-mediated neuronal cell death, TNF-alpha, hypoxia-, UV-, and staurosporine-mediated cell death but not ER stress-mediated cell death. Acts by preventing activation of caspases CASP1 and CASP4, possibly by preventing the interaction between CASP1 and RIPK2.Synonyms: CARD only domain-containing protein 1, Caspase recruitment domain-containing protein 16, Caspase-1 inhibitor COP, PSEUDO-ICE, Pseudo interleukin-1 beta converting enzyme
    分子量
    22625 Da
    基因ID
    114769
    NCBI登录号
    NP_001017534
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