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CARD16 抗体

CARD16 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7244684
发货至: 中国
  • 抗原 See all CARD16 抗体
    CARD16 (Caspase Recruitment Domain Family, Member 16 (CARD16))
    适用
    宿主
    • 21
    • 4
    • 1
    克隆类型
    • 24
    • 2
    多克隆
    标记
    • 12
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CARD16 antibody is un-conjugated
    应用范围
    • 15
    • 12
    • 9
    • 4
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
    产品特性
    Polyclonal Antibody
    纯化方法
    Antigen affinity purification
    免疫原
    Synthetic peptide of human CARD16
    亚型
    IgG
  • 应用备注
    WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.1 mg/mL
    缓冲液
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    CARD16 (Caspase Recruitment Domain Family, Member 16 (CARD16))
    别名
    CARD16 (CARD16 产品)
    别名
    COP antibody, COP1 antibody, PSEUDO-ICE antibody, caspase recruitment domain family member 16 antibody, CARD16 antibody
    背景
    Caspase inhibitor. Acts as a regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-interleukin-1 beta (IL1B) and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. Also induces NF-kappa-B activation during the pro-inflammatory cytokine response. Also able to inhibit CASP1-mediated neuronal cell death, TNF-alpha, hypoxia-, UV-, and staurosporine-mediated cell death but not ER stress-mediated cell death. Acts by preventing activation of caspases CASP1 and CASP4, possibly by preventing the interaction between CASP1 and RIPK2.
    分子量

    Observed_MW: Refer to figures

    Calculated_MW: 23 kDa

    UniProt
    Q5EG05
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