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CD45 抗体

PTPRC 适用: Cow FACS, IP, ICC 宿主: 小鼠 Monoclonal IVA103 unconjugated
产品编号 ABIN94134
发货至: 中国
  • 抗原 See all CD45 (PTPRC) 抗体
    CD45 (PTPRC) (Protein tyrosine Phosphatase, Receptor Type, C (PTPRC))
    适用
    • 347
    • 208
    • 79
    • 29
    • 20
    • 16
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    Cow
    宿主
    • 245
    • 160
    • 137
    • 2
    • 1
    小鼠
    克隆类型
    • 409
    • 128
    • 1
    单克隆
    标记
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    This CD45 antibody is un-conjugated
    应用范围
    • 443
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    Flow Cytometry (FACS), Immunoprecipitation (IP), Immunocytochemistry (ICC)
    特异性
    The antibody IVA103 reacts with an extracellular epitope of CD45R antigen (bovine), a single chain type I transmembrane glycoprotein (member of the protein tyrosine phosphatase family), a restricted form of the CD45 family. CD45R is an essential regulator of T and B lymphocytes antigen receptor signaling and it is specifically expressed in hematopoietic cells.
    交叉反应 (详细)
    Bovine
    纯化方法
    Purified by protein-A affinity chromatography.
    纯度
    > 95 % (by SDS-PAGE)
    免疫原
    Bovine leukocytes.
    克隆位点
    IVA103
    亚型
    IgG1
    Top Product
    Discover our top product PTPRC Primary Antibody
  • 应用备注
    Flow cytometry: Recommended dilution: 1-4 μg/mL.
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Do not freeze.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Do not freeze.
  • "Proceedings of the 3rd workshop on ruminant leukocyte antigens. Davis, California, 16 July 1995." in: Veterinary immunology and immunopathology, Vol. 52, Issue 4, pp. 213-468, (1997) (PubMed).

    Naessens, Howard, Hopkins: "Nomenclature and characterization of leukocyte differentiation antigens in ruminants." in: Immunology today, Vol. 18, Issue 8, pp. 365-8, (1997) (PubMed).

    Sopp, Howard: "Investigation of PC36 (BoCD45R)." in: Veterinary immunology and immunopathology, Vol. 52, Issue 4, pp. 271-4, (1997) (PubMed).

  • 抗原
    CD45 (PTPRC) (Protein tyrosine Phosphatase, Receptor Type, C (PTPRC))
    别名
    CD45R (PTPRC 产品)
    别名
    PTPRC antibody, si:dkeyp-47c5.1 antibody, B220 antibody, CD45 antibody, CD45R antibody, GP180 antibody, L-CA antibody, LCA antibody, LY5 antibody, T200 antibody, Cd45 antibody, Ly-5 antibody, Lyt-4 antibody, loc antibody, Lca antibody, RT7 antibody, cd45 antibody, protein tyrosine phosphatase, receptor type C antibody, protein tyrosine phosphatase, receptor type, C antibody, receptor-type tyrosine-protein phosphatase C antibody, PTPRC antibody, ptprc antibody, LOC100074271 antibody, Ptprc antibody
    背景
    CD45R, also known as B220, is a receptor-type protein tyrosine phosphatase glycoprotein. It is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases, promotes cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis. CD45R expression also identifies a subset of murine bone marrow cells able to form osteoclast-like cells.,PTPRCR, T200R
    途径
    TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, CXCR4-mediated Signaling Events, BCR Signaling
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