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TLR3 抗体

TLR3 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN920707
发货至: 中国
  • 抗原 See all TLR3 抗体
    TLR3 (Toll-Like Receptor 3 (TLR3))
    适用
    • 96
    • 63
    • 31
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    宿主
    • 84
    • 29
    • 3
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    小鼠
    克隆类型
    • 87
    • 31
    单克隆
    标记
    • 50
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    • 2
    • 2
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    This TLR3 antibody is un-conjugated
    应用范围
    • 81
    • 40
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    • 23
    • 15
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    Western Blotting (WB), Flow Cytometry (FACS)
    特异性
    Reacts with TLR3.
    过滤
    0.2 μm filtered
    亚型
    IgG1
    Top Product
    Discover our top product TLR3 Primary Antibody
  • 应用备注
    Flow cytometry: (intracellular) Use at a 1:10 dilution. Western blot: Use at a 1:10 dilution.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    1 mL of 0.2 µm sterile filtered antibody solution at 100 µg/mL in PBS containing 0.1% protein stabilizer.
    储存条件
    4 °C
  • 抗原
    TLR3 (Toll-Like Receptor 3 (TLR3))
    别名
    TLR3 (TLR3 产品)
    别名
    CD283 antibody, IIAE2 antibody, AI957183 antibody, zgc:123006 antibody, toll like receptor 3 antibody, toll-like receptor 3 antibody, TLR3 antibody, Tlr3 antibody, tlr3 antibody
    背景
    Toll-like receptors (TLR) are highly conserved throughout evolution and have been implicated in the innate defence to many pathogens. In Drosophila toll is required for the anti-fungal response, while the related 18-wheeler is involved in antibacterial defences. In mammals, TLR identified as type I transmembrane signalling receptors with pattern recognition capabilies, have been implicated in the innate host defence to pathogens. As investigated so far all functional characterized TLR signal via the TLR/IL-1 receptor (IL-1R) pathway where recruitment of MyD88 seems to be essential. Viral replication within infected cells results in generation of dsRNA which can stimulate immune cells. Recent data show that TLR3 acts as a receptor involved in the recognition of dsRNA, indicating a role for TLR3 in viral recognition and innate defence.
    途径
    TLR signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
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