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TRPV4 抗体 (AA 301-400) (FITC)

TRPV4 适用: 人, Cow WB, FACS 宿主: 兔 Polyclonal FITC
产品编号 ABIN918766
发货至: 中国
  • 抗原 See all TRPV4 抗体
    TRPV4 (Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4))
    抗原表位
    • 15
    • 14
    • 8
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 301-400
    适用
    • 59
    • 25
    • 24
    • 20
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, Cow
    宿主
    • 59
    • 2
    • 1
    • 1
    克隆类型
    • 62
    • 1
    多克隆
    标记
    • 30
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TRPV4 antibody is conjugated to FITC
    应用范围
    • 50
    • 25
    • 16
    • 14
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    交叉反应
    Cow, 人
    预测反应
    Mouse,Rat,Dog,Cow,Pig,Chicken
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human TRPV4
    亚型
    IgG
    Top Product
    Discover our top product TRPV4 Primary Antibody
  • 应用备注
    FCM 1:20-100
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    TRPV4 (Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4))
    别名
    TRP12 (TRPV4 产品)
    别名
    wu:fp52e02 antibody, CMT2C antibody, HMSN2C antibody, OTRPC4 antibody, SMAL antibody, SPSMA antibody, SSQTL1 antibody, TRP12 antibody, VRL2 antibody, VROAC antibody, 0610033B08Rik antibody, Trp12 antibody, VR-OAC antibody, VRL-2 antibody, Otrpc4 antibody, Vroac antibody, transient receptor potential cation channel, subfamily V, member 4 antibody, transient receptor potential cation channel subfamily V member 4 antibody, trpv4 antibody, TRPV4 antibody, Trpv4 antibody
    背景

    Synonyms: SMAL, VRL2, BCYM3, CMT2C, SPSMA, TRP12, VROAC, HMSN2C, OTRPC4, SSQTL1, Transient receptor potential cation channel subfamily V member 4, TrpV4, Osm-9-like TRP channel 4, Transient receptor potential protein 12, Vanilloid receptor-like channel 2, Vanilloid receptor-like protein 2, VRL-2, Vanilloid receptor-related osmotically-activated channel, VR-OAC

    Background: Non-selective calcium permeant cation channel probably involved in osmotic sensitivity and mechanosensitivity. Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification. Also activated by low pH , citrate and phorbol esters. Increase of intracellular Ca(2+) potentiates currents. Channel activity seems to be regulated by a calmodulin-dependent mechanism with a negative feedback mechanism. Promotes cell-cell junction formation in skin keratinocytes and plays an important role in the formation and/or maintenance of functional intercellular barriers. Acts as a regulator of intracellular Ca(2+) in synoviocytes. Plays an obligatory role as a molecular component in the nonselective cation channel activation induced by 4-alpha-phorbol 12,13-didecanoate and hypotonic stimulation in synoviocytes and also regulates production of IL-8.

    基因ID
    59341
    UniProt
    Q9HBA0
    途径
    Hormone Transport, Cell-Cell Junction Organization
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